TBC1D7 and HOOK1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TBC1D7	HOOK1
Description		TBC1 domain family member 7	hook microtubule tethering protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoplasmic Vesicle Ciliary Basal Body	Cytoplasm Centrosome Cytosol Microtubule FHF Complex
	Molecular Function	GTPase Activator Activity Protein Binding Small GTPase Binding	Actin Binding Protein Binding Microtubule Binding Identical Protein Binding Protein Homodimerization Activity Dynein Light Intermediate Chain Binding
	Biological Process	Positive Regulation Of Protein Ubiquitination Negative Regulation Of TOR Signaling Positive Regulation Of GTPase Activity Response To Growth Factor Activation Of GTPase Activity Negative Regulation Of Cilium Assembly	Golgi Organization Endosome Organization Lysosome Organization Endosome To Lysosome Transport Protein Transport Cytoskeleton-dependent Intracellular Transport Cytoplasmic Microtubule Organization Early Endosome To Late Endosome Transport Manchette Assembly Protein Localization To Perinuclear Region Of Cytoplasm
Pathways		TBC/RABGAPs
Drugs
Diseases
GWAS		Migraine ( 23793025) Migraine without aura ( 23793025)	Alcoholic chronic pancreatitis ( 28754779) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917)
Interacting Genes		30 interacting genes: AKT1 ALOX5 APP BAG4 BLZF1 GABARAPL1 HOOK1 IKBKG INCA1 KEAP1 KRT19 KRT35 LDOC1 LNX2 LZTS1 LZTS2 MAP1LC3A MIPOL1 MMADHC NEDD4 NEDD4L PICK1 RPGRIP1 SH3GLB2 SSNA1 TRAF4 TRIM62 TSC1 XPA YWHAZ	34 interacting genes: AKTIP ANK3 ANKRD23 CDC5L CDK4 CWF19L2 ERI3 FAM161A FHIP1B HOOK2 HOOK3 LMO2 MEOX2 MRPL37 MYSM1 PIAS2 S100A7 SYCE1 TBC1D7 TFIP11 USP2 UTP14C VPS16 VPS18 VPS39 VPS41 ZBTB47 ZNF250 ZNF35 ZNF572 ZNF655 ZNF764 ZNF785 ZNF80
Entrez ID		51256	51361
HPRD ID		18165	07428
Ensembl ID		ENSG00000145979	ENSG00000134709
Uniprot IDs		A0A024QZX0 A0A024R011 Q5JPB9 Q9P0N9 U3KPY5	Q9UJC3
PDB IDs		3QWL 4Z6Y 5EJC 5ULO 7DL2
Enriched GO Terms of Interacting Partners?
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