CHCHD2 and RNF144B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CHCHD2	RNF144B
Description		coiled-coil-helix-coiled-coil-helix domain containing 2	ring finger protein 144B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Intermembrane Space	Ubiquitin Ligase Complex Cytoplasm Cytosol Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding Sequence-specific DNA Binding DNA-binding Transcription Factor Binding	Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Conjugating Enzyme Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Mitochondrion Organization Cellular Response To Oxidative Stress Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Cellular Response To Hypoxia Positive Regulation Of Mitochondrial ATP Synthesis Coupled Electron Transport	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Apoptotic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Apoptotic Process
Pathways		Mitochondrial protein import	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Macular telangiectasia type 2 ( 33654266) Metabolite levels ( 23823483 31628463) Plasma free amino acid levels ( 30659259) Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259)	Adult body size ( 32376654) Age at voice drop ( 27182965) Caudal middle frontal gyrus volume ( 31530798) Chronic periodontitis (mean interproximal clinical attachment level) ( 27601451) Chronotype ( 30696823) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) Endometriosis ( 23472165) Facial morphology ( 31763980) General risk tolerance (MTAG) ( 30643258) Gut microbiota relative abundance (Dorea) ( 33208821) Pulse pressure ( 30224653) Thiopurine S-methyltransferase activity ( 27770449) Triglyceride levels ( 32203549)
Interacting Genes		31 interacting genes: ADAMTSL4 ADRA2C CHCHD10 CRYBA1 CTAG1A CTAG1B CYSRT1 EHMT2 FBXO7 GOLGA2 IKZF3 INCA1 KRT31 KRT40 LHX4 MIF4GD OIP5 P4HB PBX4 PLEKHF2 POLDIP2 REL RNF144B TCF4 TRAF2 TREX1 TRIM42 TRIM54 TSC1 USP54 ZMYND12	29 interacting genes: ANKS1A CDKN1A CHCHD2 CREB5 DTNBP1 FOXH1 IL16 OTX1 PAN2 PAX5 PRKAB2 PROP1 PRR35 RIPPLY1 SGTA SGTB TRAF4 UBC UBE2I UBE2L3 UBE2L6 UBE2T UBE2U UBE2Z UBQLN1 USP15 USP2 VENTX ZIC1
Entrez ID		51142	255488
HPRD ID		09879	17126
Ensembl ID		ENSG00000106153	ENSG00000137393
Uniprot IDs		Q9Y6H1	Q7Z419
PDB IDs
Enriched GO Terms of Interacting Partners?
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