RDH11 and BLOC1S2

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		RDH11	BLOC1S2
Description		retinol dehydrogenase 11	biogenesis of lysosomal organelles complex 1 subunit 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane	Gamma-tubulin Complex Mitochondrion Lysosomal Membrane BLOC-1 Complex BORC Complex Axon Cytoplasm
	Molecular Function	NAD-retinol Dehydrogenase Activity Protein Binding Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor NADP-retinol Dehydrogenase Activity 11-cis-retinol Dehydrogenase Activity	Protein Binding Gamma-tubulin Binding
	Biological Process	Retinoid Metabolic Process Retinol Metabolic Process Retinal Metabolic Process Cellular Detoxification Of Aldehyde	Anterograde Axonal Transport Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Endosomal Transport Neuron Projection Development Lysosome Localization Melanosome Organization Anterograde Synaptic Vesicle Transport Platelet Dense Granule Organization Mitochondrial Outer Membrane Permeabilization
Pathways		The canonical retinoid cycle in rods (twilight vision) RA biosynthesis pathway Retinoid metabolism and transport
Drugs		Vitamin A
Diseases
GWAS			Refractive error ( 32231278)
Interacting Genes		5 interacting genes: BLOC1S2 CA12 ROBO2 SELENOF TMEM31	35 interacting genes: APP ARFIP2 BFSP2 BLOC1S1 BLOC1S3 BLOC1S4 BLOC1S5 BLOC1S6 C8orf33 CCDC146 CCHCR1 CCNC CTNNA3 DCTN2 ERP27 EXOC8 FAM161B FAM9B GADD45G GEM HMOX2 KRT26 MEST P4HA3 PAM16 PICK1 RDH11 SH2D4A SNAPIN SSC5D STX2 TNNT1 TRIML2 WASHC1 WASHC3
Entrez ID		51109	282991
HPRD ID		09707	12526
Ensembl ID		ENSG00000072042	ENSG00000196072
Uniprot IDs		A0A0S2Z583 Q8TC12	A0A087X1N6 F1T0F0 Q6QNY1
PDB IDs
Enriched GO Terms of Interacting Partners?
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