TXNDC12 and FKBP7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TXNDC12	FKBP7
Description		thioredoxin domain containing 12	FKBP prolyl isomerase 7
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen	Endoplasmic Reticulum Endoplasmic Reticulum Lumen
	Molecular Function	Protein Binding Protein-disulfide Reductase Activity Protein-disulfide Reductase (glutathione) Activity	Peptidyl-prolyl Cis-trans Isomerase Activity Calcium Ion Binding Protein Binding FK506 Binding
	Biological Process	Negative Regulation Of Cell Death Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway	Protein Peptidyl-prolyl Isomerization Peptidyl-proline Modification
Pathways
Drugs
Diseases
GWAS			Alanine aminotransferase levels ( 33547301) Aspartate aminotransferase levels ( 33547301) Atrial fibrillation ( 30061737) Blood protein levels ( 30072576 29875488) Rapid functional decline in sporadic amyotrophic lateral sclerosis ( 26746183) Refractive error ( 32231278)
Interacting Genes		9 interacting genes: CAMLG DPF2 FKBP7 KLHL2 SGTA SGTB UBQLN1 UBQLN2 ZDHHC17	81 interacting genes: ABHD16A ADIPOQ AGPS AP1M1 APOD ASPH BMP10 BRICD5 CDIPT CERCAM CIAO2A CLCA4 CLDN19 CTSA CXCL16 DIABLO FAM3C FARS2 GET3 H4C7 HHATL HSBP1L1 IER3 IFITM3 IRF2 JOSD2 LAT MAN2B2 MIEF2 MRM1 NFU1 NPFFR2 OCIAD1 OXNAD1 PBX3 PCYT1A PDE11A PEX19 PLPP6 PPIF PRMT6 PTCD1 PTPN9 RBFA RBM45 RPRM RUSF1 SGTA SLC38A7 SLC7A14 SNX1 SNX12 STX7 STX8 SUCLA2 TARS2 TCP11X2 THAP4 THSD7B TMEM108 TMEM120B TMEM229B TMEM239 TMEM54 TMEM86A TMEM86B TMEM97 TRAM1L1 TSPAN2 TTC30A TTC30B TTPA TXNDC12 UBIAD1 UBQLN4 UPK1B VSTM4 WFDC2 WIPI2 YIPF6 ZFPL1
Entrez ID		51060	51661
HPRD ID		11633	08451
Ensembl ID		ENSG00000117862	ENSG00000079150
Uniprot IDs		O95881	Q9Y680
PDB IDs		1SEN 2K8V
Enriched GO Terms of Interacting Partners?
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