FIS1 and PIGP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FIS1	PIGP
Description		fission, mitochondrial 1	phosphatidylinositol glycan anchor biosynthesis class P
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Peroxisome Peroxisomal Membrane Integral Component Of Peroxisomal Membrane Endoplasmic Reticulum Cytosol Membrane Integral Component Of Mitochondrial Outer Membrane Protein-containing Complex	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Identical Protein Binding Protein-containing Complex Binding	Protein Binding Phosphatidylinositol N-acetylglucosaminyltransferase Activity
	Biological Process	Mitochondrial Fission Autophagy Of Mitochondrion Release Of Cytochrome C From Mitochondria Protein Targeting To Mitochondrion Positive Regulation Of Cytosolic Calcium Ion Concentration Mitochondrial Fusion Regulation Of Mitochondrion Organization Response To Muscle Activity Peroxisome Fission Response To Nutrient Levels Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Calcium-mediated Signaling Using Intracellular Calcium Source Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Neuron Apoptotic Process Mitochondrial Fragmentation Involved In Apoptotic Process Positive Regulation Of Mitochondrial Calcium Ion Concentration Mitochondrion Morphogenesis Cellular Response To Glucose Stimulus Positive Regulation Of Mitochondrial Fission Positive Regulation Of Protein Targeting To Membrane Cellular Response To Toxic Substance Cellular Response To Peptide Response To Fluoride Negative Regulation Of ATP Metabolic Process Cellular Response To Thapsigargin Response To Flavonoid Response To Hypobaric Hypoxia Negative Regulation Of Fatty Acid Transport Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	GPI Anchor Biosynthetic Process
Pathways		Class I peroxisomal membrane protein import	Synthesis of glycosylphosphatidylinositol (GPI)
Drugs
Diseases
GWAS		Rheumatoid arthritis ( 30891314)
Interacting Genes		31 interacting genes: A2M ABHD6 APH1A BCAP31 CREB3 DNM1L EBP ERGIC3 FAM209A FAM210B FFAR2 JAGN1 KASH5 KCNJ6 KMT2E MARCHF5 MMGT1 NOS3 PIGP RNASEK SCN3B SLC10A6 SLC14A1 SLC22A1 SLC22A2 SPCS1 TBC1D15 TMEM14B TMPPE UBC VKORC1	20 interacting genes: C1GALT1 C5 DHRSX DOP1B FIS1 IER3IP1 ITGAM LHFPL3 NINJ2 PLP1 PLP2 PTPN1 SCAMP5 SMAGP THSD7B TMEM107 TMEM19 TMEM229B UBIAD1 VPS26C
Entrez ID		51024	51227
HPRD ID		12352	05806
Ensembl ID		ENSG00000214253	ENSG00000185808
Uniprot IDs		Q9Y3D6	P57054
PDB IDs		1NZN 1PC2
Enriched GO Terms of Interacting Partners?
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