AMDHD2 and GNPDA2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid, two hybrid)

		AMDHD2	GNPDA2
Description		amidohydrolase domain containing 2	glucosamine-6-phosphate deaminase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol	Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Binding N-acetylglucosamine-6-phosphate Deacetylase Activity Metal Ion Binding N-acetylgalactosamine-6-phosphate Deacetylase Activity	Glucosamine-6-phosphate Deaminase Activity Protein Binding Identical Protein Binding
	Biological Process	Carbohydrate Metabolic Process N-acetylglucosamine Catabolic Process UDP-N-acetylglucosamine Biosynthetic Process N-acetylneuraminate Catabolic Process	Carbohydrate Metabolic Process Glucosamine Catabolic Process N-acetylglucosamine Catabolic Process UDP-N-acetylglucosamine Biosynthetic Process N-acetylneuraminate Catabolic Process
Pathways		Synthesis of UDP-N-acetyl-glucosamine	Glycolysis
Drugs
Diseases
GWAS			Adult body size ( 32376654) BMI (adjusted for smoking behaviour) ( 28443625) BMI at adiposity rebound ( 31840077) BMI in non-smokers ( 28443625) BMI in smokers ( 28443625) Body mass index ( 23563607 19079261 26961502 23669352 24861553 31453325 28892062 25673413 20935630 23583978 28448500) Body mass index (adult) ( 28430825) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Body mass index in physically inactive individuals ( 28448500) Body mass index variance ( 31453325) Body size at age 10 ( 32376654) Childhood body mass index ( 33045005 26604143) General risk tolerance (MTAG) ( 30643258) Hand grip strength ( 29691431) Hip circumference ( 25673412) Menarche (age at onset) ( 25231870) Metabolite levels ( 23823483) Obese vs. thin ( 30677029) Obesity ( 23563607) Obesity (extreme) ( 30677029) Refractive error ( 32231278) Systolic blood pressure ( 26969751) Type 2 diabetes ( 30297969 32499647 30718926) Waist circumference ( 31453325 25673412) Waist circumference variance ( 31453325)
Interacting Genes		2 interacting genes: GNPDA2 TRIP13	7 interacting genes: AMDHD2 BEND4 DCAF4L1 ERRFI1 MAGOHB NTAQ1 TRIM27
Entrez ID		51005	132789
HPRD ID		13034	13594
Ensembl ID		ENSG00000162066	ENSG00000163281
Uniprot IDs		A0A3B3IU33 Q9Y303	A0A024R9X5 Q8TDQ7
PDB IDs
Enriched GO Terms of Interacting Partners?
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