MED31 and GSTM4

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MED31	GSTM4
Description		mediator complex subunit 31	glutathione S-transferase mu 4
Image		No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleoplasm Mediator Complex Core Mediator Complex	Cytoplasm Cytosol Intercellular Bridge
	Molecular Function	Transcription Coregulator Activity Protein Binding Ubiquitin Protein Ligase Activity	Glutathione Transferase Activity Leukotriene-C4 Synthase Activity Protein Binding Enzyme Binding Protein Homodimerization Activity Glutathione Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Protein Ubiquitination Negative Regulation Of Fibroblast Proliferation Limb Development	Glutathione Metabolic Process Nitrobenzene Metabolic Process Xenobiotic Catabolic Process Long-chain Fatty Acid Biosynthetic Process
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	Glutathione conjugation Biosynthesis of maresin conjugates in tissue regeneration (MCTR)
Drugs			Glutathione Glutathione sulfonic acid S-octylglutathione Glutathione disulfide gamma-Glutamyl[S-(2-iodobenzyl)cysteinyl]glycine 1-Hydroxy-2-S-glutathionyl-3-para-nitrophenoxy-propane S-Hexylglutathione
Diseases
GWAS		LDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883)	Alcohol dependence ( 33290381) Seasonality and depression ( 30217971)
Interacting Genes		59 interacting genes: AGR2 ANXA7 ASCC2 CACNB4 CCT7 CDKN1A CPE DAZAP2 DLEU1 DNM1 EEF1G EGR2 EPN1 ERH FAM118B GADD45G GSTM4 HGH1 HMOX2 HNRNPUL1 HSPB1 HSPB3 HTT LAMA4 LYPLA2 MAFG MED18 MED19 MED7 MED8 MED9 MOB4 NAF1 NFATC2 NR4A1 ORAI2 PABPC4 PAFAH1B3 PFDN1 PMF1 PQBP1 PRMT1 PSMD11 RAB25 RBM23 RFC5 RPA2 SAT1 SELENBP1 SERPINB9 SMN1 TGIF1 TINAGL1 TK1 TLE5 UBE2B WDCP ZBTB45 ZSCAN1	11 interacting genes: APLP1 GSTM3 GSTM5 IGSF21 LRIF1 MED31 NELFCD TLE1 TP53 UNC119 ZBTB16
Entrez ID		51003	2948
HPRD ID		14382	00706
Ensembl ID		ENSG00000108590	ENSG00000168765
Uniprot IDs		Q9Y3C7	A0A140VKE3 Q03013
PDB IDs			4GTU
Enriched GO Terms of Interacting Partners?
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