ACOX1 and SLC2A4

Number of citations of the paper that reports this interaction (PubMedID 16396496)
30

Data Source:
HPRD (in vivo)

		ACOX1	SLC2A4
Description		acyl-CoA oxidase 1	solute carrier family 2 member 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Membrane Peroxisomal Matrix Cytosol Membrane	Multivesicular Body Trans-Golgi Network Cytosol Plasma Membrane Integral Component Of Plasma Membrane Clathrin-coated Pit External Side Of Plasma Membrane Endomembrane System Vesicle Membrane Membrane Sarcoplasmic Reticulum Clathrin-coated Vesicle Trans-Golgi Network Transport Vesicle T-tubule Cytoplasmic Vesicle Membrane Insulin-responsive Compartment Sarcolemma Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Exosome Presynapse
	Molecular Function	Acyl-CoA Oxidase Activity Fatty Acid Binding Palmitoyl-CoA Oxidase Activity PDZ Domain Binding Protein Homodimerization Activity Protein N-terminus Binding Flavin Adenine Dinucleotide Binding FAD Binding	Glucose Transmembrane Transporter Activity Protein Binding D-glucose Transmembrane Transporter Activity
	Biological Process	Very Long-chain Fatty Acid Metabolic Process Generation Of Precursor Metabolites And Energy Lipid Metabolic Process Prostaglandin Metabolic Process Spermatogenesis Fatty Acid Catabolic Process Fatty Acid Oxidation Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Hydrogen Peroxide Biosynthetic Process Lipid Homeostasis Very Long-chain Fatty Acid Beta-oxidation	Carbohydrate Metabolic Process Learning Or Memory Short-term Memory Long-term Memory Amylopectin Biosynthetic Process Positive Regulation Of Brain-derived Neurotrophic Factor Receptor Signaling Pathway Cellular Response To Insulin Stimulus Glucose Homeostasis Glucose Import In Response To Insulin Stimulus Response To Ethanol Glucose Import Brown Fat Cell Differentiation Cellular Response To Tumor Necrosis Factor Cellular Response To Hypoxia Cellular Response To Osmotic Stress Regulation Of Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Transport Across Blood-brain Barrier Glucose Transmembrane Transport
Pathways		Peroxisomal protein import Peroxisomal protein import TYSND1 cleaves peroxisomal proteins	Translocation of SLC2A4 (GLUT4) to the plasma membrane Cellular hexose transport Transcriptional regulation of white adipocyte differentiation
Drugs		Flavin adenine dinucleotide (3R)-3-HYDROXYDODECANOIC ACID
Diseases
GWAS		Body mass index ( 28552196) Diastolic blood pressure ( 27841878) Mean platelet volume ( 32888494) Pulse pressure ( 27841878) Systolic blood pressure ( 28135244 27841878) Urinary metabolite levels in chronic kidney disease ( 31959995) White matter hyperintensity burden ( 25663218)	Alanine aminotransferase levels ( 33547301 34315874) Apolipoprotein B levels ( 32203549) Aspartate aminotransferase levels ( 33547301 34315874) Birth weight ( 23202124 31043758) Diastolic blood pressure ( 28135244) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Liver enzyme levels (alanine transaminase) ( 33972514) Medication use (diuretics) ( 31015401) Metabolite levels ( 22286219) Offspring birth weight ( 31043758) Pulse pressure ( 28135244) Systolic blood pressure ( 30578418) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Two-hour glucose ( 34059833)
Interacting Genes		4 interacting genes: OGT SCP2 SLC2A4 TYSND1	40 interacting genes: ACOX1 ACTN1 ACTN4 AKT2 AP1M1 ARF3 ARFIP1 BSG C1QTNF5 CCDC116 CFL1 CREB3 CTSD DAXX DLD EHD2 ESYT2 FAR1 FKBP10 GAPDH HADH HK2 HSP90AA1 IDH2 KLHL41 LNPEP MAP1S MVP P3H1 P3H4 PDIA6 PRKAR1A PSMD7 RAB7A SERPINH1 SRFBP1 STRN3 UBA52 UBE2I UBE2N
Entrez ID		51	6517
HPRD ID		02030	00688
Ensembl ID		ENSG00000161533	ENSG00000181856
Uniprot IDs		Q15067	P14672
PDB IDs
Enriched GO Terms of Interacting Partners?
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