PAWR and ATP5F1C

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
HPRD (two hybrid)

		PAWR	ATP5F1C
Description		pro-apoptotic WT1 regulator	ATP synthase F1 subunit gamma
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm Actin Filament Plasma Membrane Actin Cytoskeleton	Mitochondrial Proton-transporting ATP Synthase Complex, Catalytic Sector F(1) Mitochondrion Mitochondrial Inner Membrane Mitochondrial Proton-transporting ATP Synthase Complex Mitochondrial Matrix Membrane
	Molecular Function	Transcription Corepressor Activity Actin Binding Protein Binding Enzyme Binding Leucine Zipper Domain Binding	RNA Binding Protein Binding ATP Hydrolysis Activity Proton-transporting ATP Synthase Activity, Rotational Mechanism
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Process Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of B Cell Proliferation Negative Regulation Of T Cell Proliferation Positive Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Fibroblast Proliferation Negative Regulation Of T Cell Receptor Signaling Pathway Actin Filament Bundle Assembly Apoptotic Signaling Pathway Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Positive Regulation Of Cellular Senescence	Oxidative Phosphorylation ATP Biosynthetic Process ATP Synthesis Coupled Proton Transport Mitochondrial ATP Synthesis Coupled Proton Transport
Pathways			Formation of ATP by chemiosmotic coupling Cristae formation
Drugs			Quercetin 1-ACETYL-2-CARBOXYPIPERIDINE AUROVERTIN B Piceatannol N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE
Diseases
GWAS		Attention deficit hyperactivity disorder and conduct disorder ( 18951430) Brain morphology (MOSTest) ( 32665545)
Interacting Genes		16 interacting genes: AATF ATP5F1C DAPK3 DRD2 HSPA5 PML PRKCZ RRAS2 SLC5A7 SPSB1 SPSB2 SPSB4 SQSTM1 TFPT THAP1 WT1	30 interacting genes: APP ATP5F1A ATP5F1B CA12 CCND3 CCT7 CDC42 CHMP2B DPP3 DUX4 EGFR ELOF1 ERCC6 FBXO7 GATA3 GDPD2 ITIH2 MED15 MEOX2 MPP1 NDUFB3 NGEF PAWR PJA1 PNO1 POLA2 PTEN PTN SERPINA1 ZNF337
Entrez ID		5074	509
HPRD ID		09051	00156
Ensembl ID		ENSG00000177425	ENSG00000165629
Uniprot IDs		Q96IZ0	B4DL14 P36542 Q8TAS0
PDB IDs		2JK9
Enriched GO Terms of Interacting Partners?
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