PAFAH1B2 and CLVS2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PAFAH1B2	CLVS2
Description		platelet activating factor acetylhydrolase 1b catalytic subunit 2	clavesin 2
Image			No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Extracellular Region Nucleolus Cytoplasm Cytosol Plasma Membrane 1-alkyl-2-acetylglycerophosphocholine Esterase Complex Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen	Endosome Trans-Golgi Network Clathrin-coated Vesicle Early Endosome Membrane Trans-Golgi Network Membrane
	Molecular Function	1-alkyl-2-acetylglycerophosphocholine Esterase Activity Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding Protein Heterodimerization Activity Platelet-activating Factor Acetyltransferase Activity	Protein Binding Phosphatidylinositol-3,5-bisphosphate Binding Phosphatidylinositol Bisphosphate Binding
	Biological Process	Lipid Metabolic Process Spermatogenesis Brain Development Lipid Catabolic Process Positive Regulation Of Macroautophagy	Lysosome Organization
Pathways		Neutrophil degranulation COPI-independent Golgi-to-ER retrograde traffic	Lysosome Vesicle Biogenesis
Drugs
Diseases
GWAS		Adult body size ( 32376654) Blood protein levels ( 28240269 23696881) HDL cholesterol ( 24507774) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Protein quantitative trait loci ( 18464913) Refractive error ( 32231278) Systolic blood pressure ( 30578418)	Refractive error ( 32231278) Triglyceride levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder ( 33824429)
Interacting Genes		20 interacting genes: ACIN1 ASF1A CCT3 CLVS2 CRK KMT2A PAFAH1B1 PAFAH1B3 PINX1 PPP1R12C PRKN REXO1 RPLP0 SLA SNUPN STAT3 TIMM50 TRIM55 TRIM63 ZFP36L1	17 interacting genes: EMSY FBXW2 FLAD1 GSTM3 GSTZ1 GYS1 KAZN MEOX2 MYH7 PAFAH1B2 PCYT2 PGAM2 PHETA2 S100A7 S100A7A TACC2 TBC1D32
Entrez ID		5049	134829
HPRD ID		03940	16666
Ensembl ID		ENSG00000168092	ENSG00000146352
Uniprot IDs		P68402 V9HW44	Q5SYC1
PDB IDs		1VYH
Enriched GO Terms of Interacting Partners?
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