MS4A13 and BEST1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MS4A13	BEST1
Description		membrane spanning 4-domains A13	bestrophin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Cytosol Plasma Membrane Basal Plasma Membrane Membrane Integral Component Of Membrane Basolateral Plasma Membrane Chloride Channel Complex
	Molecular Function	Protein Binding	Intracellular Calcium Activated Chloride Channel Activity Chloride Channel Activity Bicarbonate Transmembrane Transporter Activity Identical Protein Binding
	Biological Process		Chloride Transport Visual Perception Bicarbonate Transport Transepithelial Chloride Transport Ion Transmembrane Transport Detection Of Light Stimulus Involved In Visual Perception Regulation Of Calcium Ion Transport Chloride Transmembrane Transport
Pathways			Stimuli-sensing channels
Drugs
Diseases
GWAS		Congenital heart disease (maternal effect) ( 28468790) Major depressive disorder ( 29317602) Metabolite levels (X-11787) ( 23934736)	Aspartate aminotransferase levels ( 33547301) Estradiol levels ( 22675492) Metabolite levels ( 23823483) Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid) ( 21829377) Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid) ( 21829377) Plasma omega-6 polyunsaturated fatty acid levels (adrenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311) Red blood cell fatty acid levels ( 25500335)
Interacting Genes		61 interacting genes: AQP2 AQP6 ASGR2 ATP6V0E1 BEST1 BIK CBARP CD79A CLDN7 CREB3L1 CREB3L3 DAGLA EBP EDA EREG ERGIC3 EVA1A FAM209A FAM210B FFAR2 GJA4 GJA5 GJA8 GJB1 GJB5 GJB6 GJC3 GPR152 HERPUD2 JSRP1 KCNMB4 KLRC1 LHFPL5 LRRC3B MMGT1 MS4A3 NPDC1 ODF4 POMK RAMP1 RHCG RNF185 SCN3B SLC12A7 SLC13A4 SLC16A2 SLC18A1 SLC30A2 SLC39A2 SLC7A1 SPAG4 SSMEM1 TBXA2R TLCD4 TM4SF18 TMC4 TMEM14B TMEM237 TMEM52B TMEM74 VSIR	4 interacting genes: FXYD6-FXYD2 MS4A13 PPP2CA PPP2R5A
Entrez ID		503497	7439
HPRD ID		17604	01094
Ensembl ID		ENSG00000204979	ENSG00000167995
Uniprot IDs		Q5J8X5	A0A0S2Z4M4 A0A0S2Z579 B7Z1N8 B7Z375 O76090
PDB IDs
Enriched GO Terms of Interacting Partners?
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