ORC2 and MCM6

  • Number of citations of the paper that reports this interaction (PubMedID 12614612)
  • 25
  • Data Source:
  • BioGRID (two hybrid)
  • HPRD (in vitro, two hybrid)

ORC2

MCM6

Description origin recognition complex subunit 2 minichromosome maintenance complex component 6
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Plasma parathyroid hormone levels ( 30134803)
  • Triptolide cytotoxicity ( 26121980)
  • Aspartate aminotransferase levels ( 33547301)
  • Body fat percentage and LDL-C (pairwise) ( 33619380)
  • Body mass index ( 25673413)
  • Body mass index and LDL-C (pairwise) ( 33619380)
  • Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223)
  • Hip circumference ( 25673412)
  • Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931)
Interacting Genes 31 interacting genes: BCS1L CDC45 CDC5L CDC6 CDK2 CDT1 CTNNA3 DBF4 EP300 H3-4 H4-16 KAT7 MCM10 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 ORC1 ORC3 ORC4 ORC5 ORC6 RAD18 RFWD3 RIPPLY3 RPA1 RPA2 SHANK2 XRCC5 37 interacting genes: C2CD6 CCNA1 CDC42 CDC45 CDC7 CDKN2A CDT1 CHEK1 CRLS1 DBF4 ESCO2 FAM161A GMNN HSPB1 IL36RN ING5 MCM10 MCM2 MCM3 MCM4 MCM7 MCM8 MCMBP MLLT3 MTDH NUDT2 ORC1 ORC2 ORC4 ORC6 PSMA1 RPA1 SCNM1 SMC1A SNRPB2 TRIM28 ZBTB9
Entrez ID 4999 4175
HPRD ID 03112 03485
Ensembl ID ENSG00000115942 ENSG00000076003
Uniprot IDs A0A024R411 Q13416 Q14566
PDB IDs 5C8H 5UJ8 5UJM 7CTE 7CTF 7CTG 7JPO 7JPP 7JPQ 7JPR 7JPS 2KLQ 2LE8 6XTX 6XTY
Enriched GO Terms of Interacting Partners?
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