NTRK2 and SHC3

  • Number of citations of the paper that reports this interaction (PubMedID 9507002)
  • 24
  • Data Source:
  • HPRD (in vivo)

NTRK2

SHC3

Description neurotrophic receptor tyrosine kinase 2 SHC adaptor protein 3
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Logical memory (delayed recall) in Alzheimer's disease dementia ( 29274321)
  • Monocyte count ( 32888494)
  • Pelvic organ prolapse (moderate/severe) ( 26545240)
  • Response to statins (LDL cholesterol change) ( 22331829)
  • Superior parietal cortex volume ( 31530798)
  • Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes 38 interacting genes: AP1B1 BDNF CDK20 DOK5 DYNLL1 EGFR ERBB2 ERBB4 FRS2 FRS3 FYN GIPC1 KCNS1 KIDINS220 NCK1 NCK2 NDFIP1 NGFR NMNAT1 NTF3 NTF4 NXNL2 PIK3R1 PLCG1 POLR2G PTPN1 PTPN11 RASGRF1 SH2B1 SH2B2 SHC1 SHC2 SHC3 SORT1 SQSTM1 TRAF6 UBB USP8 58 interacting genes: ALK ANKRD10 APP AR ARHGAP32 ASPG AXL BMF CCNC CDCA4 CEACAM6 COPS6 CT55 DOK3 EGFR ERBB2 ERBB3 ERBB4 FLT4 FTO GAB1 GOLGA2 GOLGA6L9 GRB2 KIT KRT31 KRT33B KRT34 KRT35 KRT39 KRT40 KRT86 MET NTRK1 NTRK2 PMF1 PNMA1 PPP1R16B PRKAR1B PSMD8 REL RET SH3GL3 SMYD3 STX11 TRAF1 TRAF2 TRIM35 TRIM54 TSC1 UBAP2 USHBP1 USP54 VPS28 WWOX YPEL3 YPEL5 ZMYND12
Entrez ID 4915 53358
HPRD ID 02712 12005
Ensembl ID ENSG00000148053 ENSG00000148082
Uniprot IDs A0A024R230 Q16620 Q548C2 Q5VWE5 Q92529
PDB IDs 1HCF 1WWB 2MFQ 4ASZ 4AT3 4AT4 4AT5 5MO9
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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