ATP2B2 and PDZD11

Number of citations of the paper that reports this interaction (PubMedID 12763866)
18

Data Source:
HPRD (two hybrid, in vitro)

		ATP2B2	PDZD11
Description		ATPase plasma membrane Ca2+ transporting 2	PDZ domain containing 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane Apical Plasma Membrane Dendritic Spine Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome Presynapse Postsynaptic Density Membrane Glutamatergic Synapse GABA-ergic Synapse	Extracellular Region Cytosol Cell-cell Junction Adherens Junction Basolateral Plasma Membrane Synapse Pore Complex Presynapse
	Molecular Function	P-type Calcium Transporter Activity Protein Binding Calmodulin Binding ATP Binding ATP Hydrolysis Activity ATPase-coupled Cation Transmembrane Transporter Activity PDZ Domain Binding Metal Ion Binding P-type Calcium Transporter Activity Involved In Regulation Of Presynaptic Cytosolic Calcium Ion Concentration P-type Calcium Transporter Activity Involved In Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration	Protein Binding
	Biological Process	Calcium Ion Transport Cellular Calcium Ion Homeostasis Sensory Perception Of Sound Neuron Differentiation Ion Transmembrane Transport Regulation Of Cytosolic Calcium Ion Concentration Calcium Ion Transmembrane Transport Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration Regulation Of Cardiac Conduction	Neurotransmitter Secretion Maintenance Of Epithelial Cell Apical/basal Polarity Pore Complex Assembly Protein Localization To Basolateral Plasma Membrane
Pathways		Reduction of cytosolic Ca++ levels Ion homeostasis Ion transport by P-type ATPases	Biotin transport and metabolism Vitamin B5 (pantothenate) metabolism Transport of vitamins, nucleosides, and related molecules Ion influx/efflux at host-pathogen interface Ion transport by P-type ATPases
Drugs		Halothane Desflurane
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Cognitive decline rate in late mild cognitive impairment ( 26252872) Hip circumference adjusted for BMI ( 34021172) Manganese levels ( 26025379) Metabolite levels ( 19043545)
Interacting Genes		8 interacting genes: DLG1 DLG2 DLG4 ERBIN PDZD11 PRKCA SLC9A3R2 SNTA1	17 interacting genes: ATP2B2 ATP7A CD79B EDEM1 GDPD2 KIF4A MAGI2 MYO1F NLGN3 PLEKHA5 RAB11FIP2 SIGMAR1 SMG8 SNX12 TAF1 TEX11 ZMYM3
Entrez ID		491	51248
HPRD ID		00160	06622
Ensembl ID		ENSG00000157087	ENSG00000120509
Uniprot IDs		A0A024R2E4 Q01814 Q4LE63	Q5EBL8
PDB IDs
Enriched GO Terms of Interacting Partners?
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