NSF and ASPSCR1

Number of citations of the paper that reports this interaction (PubMedID 25078495)
4

Data Source:
BioGRID (pull down)

		NSF	ASPSCR1
Description		N-ethylmaleimide sensitive factor, vesicle fusing ATPase	ASPSCR1 tether for SLC2A4, UBX domain containing
Image
GO Annotations	Cellular Component	Lysosomal Membrane Golgi Apparatus Golgi Stack Cytosol Plasma Membrane Postsynaptic Density Dendritic Shaft	Nucleoplasm Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Endomembrane System Vesicle Membrane Extrinsic Component Of Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	SNARE Binding Protein Binding ATP Binding ATP Hydrolysis Activity Syntaxin-1 Binding Protein Kinase Binding PDZ Domain Binding Ionotropic Glutamate Receptor Binding Protein-containing Complex Binding Metal Ion Binding Protein Disaggregase Activity	Protein Binding
	Biological Process	Positive Regulation Of Receptor Recycling Potassium Ion Transport Intracellular Protein Transport Exocytosis Intra-Golgi Vesicle-mediated Transport Vesicle-mediated Transport Regulation Of Exocytosis SNARE Complex Disassembly Golgi To Plasma Membrane Protein Transport Plasma Membrane Fusion Positive Regulation Of Protein Catabolic Process Golgi Vesicle Docking	Intracellular Protein Transport Positive Regulation Of Protein Modification Process Glucose Homeostasis Regulation Of Glucose Import
Pathways		COPII-mediated vesicle transport Trafficking of GluR2-containing AMPA receptors COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network	Translocation of SLC2A4 (GLUT4) to the plasma membrane
Drugs		1-Ethyl-Pyrrolidine-2,5-Dione
Diseases
GWAS		Alcohol use disorder (total score) ( 30336701) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Cortical surface area ( 32963231) Cortical surface area (global PC1) ( 32198502) Cortical volume ( 32963231) General factor of neuroticism ( 30867560) Handedness (Left-handed vs. non-left-handed) ( 30980028) Handedness (Right-handed vs. non-right-handed) ( 30980028) Hemoglobin levels ( 32327693) Hypertrophic cardiomyopathy ( 33495596) Hypertrophic cardiomyopathy (MTAG) ( 33495596) Intelligence (MTAG) ( 29326435) Intraocular pressure ( 30054594) Macular thickness ( 30535121) Male-pattern baldness ( 28196072) Parkinson's disease ( 19915575 21812969) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Reaction time ( 29844566) Refractive error ( 32231278) Sense of smell ( 26632684) Thyroid stimulating hormone levels ( 30367059)	Birth weight ( 31043758) FEV1 ( 30804560) Hip circumference adjusted for BMI ( 34021172) Lung function (FVC) ( 30804560) Offspring birth weight ( 31043758) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		28 interacting genes: ARRB1 ASPSCR1 CD28 CEP126 DRD2 EIF3E ERG28 ESR1 FUNDC2 GABARAP GABARAPL2 GABBR1 GABBR2 GOSR1 GRIA2 GRIA3 LUC7L2 MEOX2 NAPA NAPG PTPN9 RAMP3 RPLP1 STX1A STX4 STX8 USO1 VAPA	15 interacting genes: ADAMTSL4 APP CLK2 INCA1 KRT31 KRTAP1-1 KRTAP10-8 NEDD4 NOTCH2NLA NSF PHAX TACC3 TCF4 VCP VCPKMT
Entrez ID		4905	79058
HPRD ID		03380	06947
Ensembl ID		ENSG00000073969	ENSG00000169696
Uniprot IDs		A0A384MTI6 P46459	Q9BZE9
PDB IDs		6KZQ	5IFS 5IFW
Enriched GO Terms of Interacting Partners?
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