NRCAM and CNTN2

Number of citations of the paper that reports this interaction (PubMedID 12139915)
23

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		NRCAM	CNTN2
Description		neuronal cell adhesion molecule	contactin 2
Image
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Neuron Projection Axon Initial Segment	Plasma Membrane Cell Surface Axon Node Of Ranvier Neuronal Cell Body Myelin Sheath Juxtaparanode Region Of Axon Synapse Anchored Component Of Postsynaptic Membrane
	Molecular Function	Protein Binding Ankyrin Binding	Protein Binding Carbohydrate Binding Identical Protein Binding Protein Self-association Cell-cell Adhesion Mediator Activity
	Biological Process	Angiogenesis Neuron Migration Axonogenesis Axon Guidance Axonal Fasciculation Synapse Assembly Central Nervous System Development Regulation Of Axon Extension Clustering Of Voltage-gated Sodium Channels Positive Regulation Of Neuron Differentiation Cell-cell Adhesion	Microtubule Cytoskeleton Organization Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Axon Guidance Axonal Fasciculation Learning Adult Walking Behavior Regulation Of Cell Morphogenesis Involved In Differentiation Positive Regulation Of Protein Processing Cerebral Cortex GABAergic Interneuron Migration Central Nervous System Myelination Regulation Of Axon Diameter Receptor Internalization Clustering Of Voltage-gated Potassium Channels Negative Regulation Of Neuron Differentiation Regulation Of Neuronal Synaptic Plasticity Regulation Of Astrocyte Differentiation Positive Regulation Of Adenosine Receptor Signaling Pathway Dendrite Self-avoidance Protein Localization To Juxtaparanode Region Of Axon Establishment Of Protein Localization To Juxtaparanode Region Of Axon Presynaptic Membrane Organization
Pathways		Interaction between L1 and Ankyrins NrCAM interactions Neurofascin interactions	L1CAM interactions NCAM1 interactions NrCAM interactions
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Coffee consumption ( 21876539) Diastolic blood pressure ( 27841878) Femoral neck bone geometry and menarche (age at onset) ( 23593202) Systolic blood pressure ( 27841878) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) White matter hyperintensities in ischemic stroke ( 26674333) White matter hyperintensity burden ( 25663218)	Adventurousness ( 30643258) Aspartate aminotransferase levels ( 33547301) Blood protein levels ( 30072576 29875488 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) HDL cholesterol levels ( 32203549) Mean platelet volume ( 24026423) Meat-related diet ( 32066663) Number of sexual partners ( 30643258) Periodontitis (stage III/IV grade C) ( 33745150) Red blood cell count ( 27863252) Schizophrenia ( 30285260) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		9 interacting genes: ANK2 CNTN2 ELOC HSPA12A LNX1 MACF1 MAGI3 NFASC PTPRB	13 interacting genes: CDK4 CHEK1 CNTN1 CNTNAP2 EGFR L1CAM NCAN NEK2 NFYB NRCAM TUBG1 UBE4B VAC14
Entrez ID		4897	6900
HPRD ID		07207	01826
Ensembl ID		ENSG00000091129	ENSG00000184144
Uniprot IDs		B7Z670 C9JYY6 Q14CA1 Q92823	A1L3A3 A1ML24 Q02246
PDB IDs		1UEN 1UEY	2OM5
Enriched GO Terms of Interacting Partners?
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