PNP and CCDC90B

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PNP	CCDC90B
Description		purine nucleoside phosphorylase	coiled-coil domain containing 90B
Image
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Cytosol Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen	Mitochondrion Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	Nucleoside Binding Purine Nucleobase Binding Purine-nucleoside Phosphorylase Activity Protein Binding Phosphate Ion Binding Identical Protein Binding Guanosine Phosphorylase Activity	Protein Binding
	Biological Process	Allantoin Metabolic Process Nucleobase-containing Compound Metabolic Process Inosine Catabolic Process Deoxyinosine Catabolic Process Deoxyadenosine Catabolic Process Purine Ribonucleoside Salvage IMP Catabolic Process Nicotinamide Riboside Catabolic Process Immune Response Nucleotide Biosynthetic Process Response To Xenobiotic Stimulus Positive Regulation Of Interleukin-2 Production Urate Biosynthetic Process Positive Regulation Of T Cell Proliferation Purine-containing Compound Salvage DAMP Catabolic Process Positive Regulation Of Alpha-beta T Cell Differentiation
Pathways		Neutrophil degranulation Purine salvage Purine catabolism
Drugs		Cladribine Didanosine 8-azaguanine 2,6-Diamino-(S)-9-[2-(Phosphonomethoxy)Propyl]Purine Immucillin-G Guanine 2-Amino-7-[2-(2-Hydroxy-1-Hydroxymethyl-Ethylamino)-Ethyl]-1,7-Dihydro-Purin-6-One Peldesine 9-deazainosine Guanosine Ribose-1-Phosphate (3R,4R)-3-Hydroxy-4-(hydroxymethyl)-1-[(4-oxo-4,4a,5,7a-tetrahydro-3H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]pyrrolidinium 3'-deoxyguanosine (2S,3R,4S,5S)-3,4-Dihydroxy-2-[(methylsulfanyl)methyl]-5-(4-oxo-4,5-dihydro-1H-pyrrolo[3,2-d]pyrimidin-7-yl)pyrrolidinium Hypoxanthine 9-(5,5-Difluoro-5-Phosphonopentyl)Guanine Inosine 9-DEAZAINOSINE-2',3'-O-ETHYLIDENEPHOSPHONATE GUANOSINE-2',3'-O-ETHYLIDENEPHOSPHONATE GUANOSINE-2',3'-O-METHYLIDENEPHOSPHONATE Forodesine
Diseases
GWAS		Alanine aminotransferase levels ( 33547301 34315874) Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Aspartate aminotransferase levels ( 33547301 34315874) Blood protein levels ( 30072576) HDL cholesterol levels ( 32203549) Interferon alpha levels in systemic lupus erythematosus ( 25338677) Menopause (age at onset) ( 26414677)	Brain morphology (MOSTest) ( 32665545) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Refractive error ( 32231278)
Interacting Genes		11 interacting genes: APLP1 CCDC90B LRIF1 NCALD NOS1AP RBM48 TFAM TFB2M TP53 UCHL5 ZHX1	31 interacting genes: AGR2 ANXA7 ARL15 BTBD2 CDKN2B CDKN2C DLEU1 DNM2 EIF2S2 FXYD6 GORASP2 KDM1A LAMTOR1 MOB2 NACA NIPSNAP3A PAFAH1B3 PCDHA4 PIN1 PNP PRDX5 PSMD11 RGL2 RNF10 SAT1 SDHAF2 SERPINB9 SMN1 TAC3 TK1 TSC22D1
Entrez ID		4860	60492
HPRD ID		01247	14378
Ensembl ID		ENSG00000198805	ENSG00000137500
Uniprot IDs		P00491 V9HWH6	Q9GZT6
PDB IDs		1M73 1PF7 1PWY 1RCT 1RFG 1RR6 1RSZ 1RT9 1ULA 1ULB 1V2H 1V3Q 1V41 1V45 1YRY 2A0W 2A0X 2A0Y 2OC4 2OC9 2ON6 2Q7O 3BGS 3D1V 3GB9 3GGS 3INY 3K8O 3K8Q 3PHB 4EAR 4EB8 4ECE 4GKA 5ETJ 5UGF	6H9M
Enriched GO Terms of Interacting Partners?
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