NME2 and BNIPL

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		NME2	BNIPL
Description		NME/NM23 nucleoside diphosphate kinase 2	BCL2 interacting protein like
Image			No pdb structure
GO Annotations	Cellular Component	Ruffle Extracellular Region Nucleus Cytoplasm Cytosol Intermediate Filament Focal Adhesion Lamellipodium Mitochondrial Membrane Secretory Granule Lumen Perinuclear Region Of Cytoplasm Extracellular Exosome Cell Periphery Ficolin-1-rich Granule Lumen	Nucleus Cytoplasm Cytosol
	Molecular Function	DNA Binding Transcription Coactivator Activity Nucleoside Diphosphate Kinase Activity Protein Histidine Kinase Activity Protein Serine/threonine Kinase Activity Fatty Acid Binding Protein Binding ATP Binding GDP Binding Intermediate Filament Binding Enzyme Binding Identical Protein Binding Metal Ion Binding G-quadruplex DNA Binding	Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Myeloid Leukocyte Differentiation Nucleoside Diphosphate Phosphorylation GTP Biosynthetic Process UTP Biosynthetic Process CTP Biosynthetic Process Cell Adhesion Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Integrin-mediated Signaling Pathway Nucleoside Triphosphate Biosynthetic Process Positive Regulation Of Neuron Projection Development Peptidyl-histidine Phosphorylation Cellular Response To Oxidative Stress Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Keratinocyte Differentiation Regulation Of Epidermis Development Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Protein Autophosphorylation Positive Regulation Of Epithelial Cell Proliferation Response To Growth Hormone Cellular Response To Glucose Stimulus Cellular Response To Fatty Acid	Apoptotic Process Negative Regulation Of Cell Population Proliferation Regulation Of Growth Rate
Pathways		Interconversion of nucleotide di- and triphosphates Neutrophil degranulation
Drugs		Guanosine-5'-Diphosphate
Diseases
GWAS		Bipolar disorder ( 31043756) Blood protein levels ( 30072576) Height ( 20881960)	Body mass index ( 26426971) Chronic kidney disease ( 20383146) Triglyceride levels x SSRI defined daily dose interaction in schizophrenia or bipolar disorder ( 33824429) Type 2 diabetes ( 30297969)
Interacting Genes		18 interacting genes: BNIPL CTBP1 DNM1 GIT2 HERC3 HERC5 HERC6 MOB4 NME1 NME3 PPP2CA RAB5A RORA RORB SVIL TBXA2R TERF1 VIM	13 interacting genes: ARHGAP1 BCL2 BCL2L1 BNIP2 FKBP8 GFER MIF NME2 PXDN PYCR1 RECQL5 RHOU SNAPIN
Entrez ID		4831	149428
HPRD ID		01132	16557
Ensembl ID		ENSG00000243678	ENSG00000163141
Uniprot IDs		F6XY72 P22392 Q6FHN3	Q7Z465
PDB IDs		1NSK 1NUE 3BBB 3BBC 3BBF
Enriched GO Terms of Interacting Partners?
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