NFE2L1 and CD6

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		NFE2L1	CD6
Description		nuclear factor, erythroid 2 like 1	CD6 molecule
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Endoplasmic Reticulum Membrane Cytosol Integral Component Of Membrane	Immunological Synapse Extracellular Region Integral Component Of Plasma Membrane External Side Of Plasma Membrane Intrinsic Component Of Plasma Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Lipid Binding Identical Protein Binding	Lipopolysaccharide Binding Scavenger Receptor Activity Protein Binding Identical Protein Binding Lipoteichoic Acid Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Heme Biosynthetic Process Cholesterol Metabolic Process Anatomical Structure Morphogenesis Cellular Response To Oxidative Stress	Immunological Synapse Formation Adaptive Immune Response Acute Inflammatory Response To Antigenic Stimulus Endocytosis Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Lipopolysaccharide-mediated Signaling Pathway Response To Lipopolysaccharide Positive Regulation Of T Cell Proliferation Innate Immune Response Positive Regulation Of Cytokine Production Involved In Inflammatory Response
Pathways
Drugs		Dodecyldimethylamine N-oxide
Diseases
GWAS		Aspartate aminotransferase levels ( 33547301) Fasting glucose ( 34059833) Generalized epilepsy ( 22949513) Heel bone mineral density ( 30598549) Hematocrit ( 32888494) Red blood cell count ( 32888494)	Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Gut microbiota (bacterial taxa) ( 27694959) Gut microbiota (functional units) ( 27694959) Inflammatory bowel disease ( 28067908 23128233) Lymphocyte counts ( 32888494) Multiple sclerosis ( 31604244 21244703 24076602 19525953 21833088) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		16 interacting genes: ATF4 BACH2 CAPN1 CD6 CREBZF GSK3B HCFC1 JUN JUNB JUND MAFF MAFG MAFK NFE2L3 PARVA TULP3	5 interacting genes: ALCAM CD5 GYG1 NFE2L1 SDCBP
Entrez ID		4779	923
HPRD ID		01223	01724
Ensembl ID		ENSG00000082641	ENSG00000013725
Uniprot IDs		J9JIE5 Q14494 Q8NF22	P30203 Q6AZ88 Q8N4Q7
PDB IDs			5A2E
Enriched GO Terms of Interacting Partners?
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