NEU1 and SLC17A2

		NEU1	SLC17A2
Description		neuraminidase 1	solute carrier family 17 member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Lysosome Lysosomal Membrane Plasma Membrane Membrane Cell Junction Specific Granule Lumen Lysosomal Lumen Intracellular Membrane-bounded Organelle Extracellular Exosome	Lysosome Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Exo-alpha-sialidase Activity Protein Binding Alpha-sialidase Activity Exo-alpha-(2->3)-sialidase Activity Exo-alpha-(2->6)-sialidase Activity Exo-alpha-(2->8)-sialidase Activity	Sodium:phosphate Symporter Activity Sialic Acid Transmembrane Transporter Activity Transmembrane Transporter Activity
	Biological Process	Ganglioside Catabolic Process Oligosaccharide Catabolic Process	Phosphate-containing Compound Metabolic Process Sodium Ion Transport Anion Transport Sialic Acid Transport Sodium Ion Transmembrane Transport
Pathways		Glycosphingolipid metabolism Sialic acid metabolism Defective NEU1 causes sialidosis Neutrophil degranulation
Drugs		Oseltamivir
Diseases
GWAS		Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Basal cell carcinoma ( 27539887) Blood protein levels ( 28240269) Body shape index ( 34021172) Estimated glomerular filtration rate ( 31152163) Inflammatory bowel disease ( 28067908) Neutrophil percentage of white cells ( 32888494) Platelet distribution width ( 32888494) Small cell lung carcinoma ( 28604730) Squamous cell lung carcinoma ( 28604730) Ulcerative colitis ( 28067908) Waist-hip index ( 34021172)	Autism spectrum disorder or schizophrenia ( 28540026) Blood pressure ( 24954895) Brain morphology (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) Height ( 25429064) Hemoglobin levels ( 32327693) Iron status biomarkers (total iron binding capacity) ( 28334935) LDL cholesterol ( 30275531) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Oily fish consumption ( 32066663) Red cell distribution width ( 32888494 27863252 28957414) Refractive error ( 32231278) Serum uric acid levels ( 32514006) Subcortical volume (MOSTest) ( 32665545) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		37 interacting genes: AQP6 CCR9 CD79A CDC42SE2 CERS3 CERS4 CREB3 CREB3L1 CTSA EBP EEF1A1 ERGIC3 ERRFI1 GLB1 GOLM1 GPR152 GPX8 HSD17B11 IGF1 JUNB KCNA2 KCNA4 LIG4 LMNA MAF MGST3 MSH5 MUC1 NFYA NOTCH4 PBX2 SLC10A1 SLC10A6 SLC17A2 SLC18A1 SLC39A9 TMEM14B	1 interacting genes: NEU1
Entrez ID		4758	10246
HPRD ID		09751	10232
Ensembl ID		ENSG00000204386	ENSG00000112337
Uniprot IDs		Q5JQI0 Q99519	A0A024QZY2 O00624
PDB IDs
Enriched GO Terms of Interacting Partners?
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