NEDD4 and IGF1R

  • Number of citations of the paper that reports this interaction (PubMedID 12697834)
  • 90
  • Data Source:
  • HPRD (in vivo)

NEDD4

IGF1R

Description NEDD4 E3 ubiquitin protein ligase insulin like growth factor 1 receptor
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Interacting Genes 242 interacting genes: ABCB1 ABL1 ABL2 ADRB2 AKT1 AKT3 AMOT AMOTL1 AMPD2 ANKRD13D ANXA13 AP1G2 ARID1A ASPSCR1 AURKC BAIAP2 BMPR1A BRCA2 CAD CALCOCO1 CAMK1D CAMK4 CAMKK2 CASP1 CASP3 CASP6 CASP7 CBLB CCNH CDC25C CDK5 CDK5R1 CLIC2 CLK3 CPSF1 CPSF6 CUEDC1 DAZAP2 DCUN1D1 DDX3X DDX54 DHX30 DIAPH1 DVL1 DYRK4 EBAG9 EGFR EPHA5 EPRS1 EPS15 ERBB3 ERBB4 ERMN ERRFI1 FES FGF12 FGF21 FGFR1 FGFR2 FKBP3 FLT1 FLT4 FYN GABARAP GABARAPL1 GABARAPL2 GBA GFUS GRB10 GRIN2A GRK4 GRK7 H3-3A HGS HMCES HNRNPK HNRNPL HNRNPU HNRNPUL1 IFITM3 IGF1R IL1B IRS1 IRS2 JHY JUN KCNAB1 KCNAB2 KCNJ16 KIFC3 LAPTM5 LATS1 LINC01198 LITAF LUC7L2 MAP1LC3A MAP1LC3B MAP1LC3C MAP3K2 MAP3K3 MAP3K5 MAP4K5 MAPKAPK3 MARK2 MARK4 MLANA MOB3A MRPL19 MTMR4 MYCN MYO15B N4BP2 N4BP3 NDFIP1 NDFIP2 NFE2 NHP2 NSRP1 NUDT21 NUMB PARP16 PAX7 PDGFRB PIP5K1A PIP5K1C PKN2 PLK1 PLK2 PMEPA1 POLR1C POLR2A POLR2B POLR2C POLR2E POLR2M POLR3A PRKG2 PRKX PRPF8 PRR16 PRRG1 PRRG2 PSMD4 PTEN PYM1 RAC1 RAD51AP1 RAF1 RANBP10 RAP2A RAPGEF2 RAPGEF6 RASGEF1A RASL11B RBCK1 RET RFT1 RNF11 RNF7 RPAP2 RPAP3 RPL18A RPS3A RPS6KA3 RPS6KA4 RPS6KB1 RUNX1 RUVBL1 SAAL1 SAMSN1 SAV1 SCAMP3 SCN5A SCNN1A SCNN1B SCNN1G SEPTIN9 SERTAD1 SFTPC SGK1 SGK2 SH3KBP1 SHISA6 SHTN1 SIVA1 SLC23A2 SLC6A3 SMAD1 SMAD3 SMAD5 SMARCC1 SMO SNCA SP140L SPANXN3 SPRY2 SQSTM1 SRC SRMS SRSF7 STK24 STK25 STK26 STK31 STK4 SULF1 SYK SYT1 TAF1B TBC1D7 TBK1 TCEANC TCP11L1 TEAD2 THOC1 THRAP3 TNIK TOM1 TOM1L2 TP53BP2 TP73 TRIM44 TRIM52 TRPV6 TTYH2 UBAP2L UBC UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2L3 UBE2M UBOX5 URI1 VDAC2 VDAC3 WBP1 WBP2 WEE1 YES1 YOD1 95 interacting genes: AMY2A APP ARHGEF12 BAP1 CAV1 CBL CDK4 CDKN2B CRK CRKL CSK CYP17A1 DOK4 DOK5 DUSP10 DUSP14 DUSP15 DUSP18 DUSP19 DUSP21 DUSP26 DUSP29 EEA1 EHD1 ERBB2 ESR1 FFAR2 FGFR4 GIPC1 GNAI1 GNAI2 GRB10 GRB14 GRM1 HOXC6 IGF1 IGF2 IGFBP3 IL13RA2 ILKAP INS INSR IRS1 IRS2 IRS4 ITGB1 JAK1 JAK2 KCNIP3 KDELR2 KL KLK5 KRT27 LYPD3 MAP3K5 MDM2 MTA3 NAT2 NEDD4 NF2 PCSK6 PIK3R1 PIK3R2 PIK3R3 PPM1A PRKCD PRKD1 PTPN1 PTPN11 PTPN12 PTPN6 PTPN7 PTPRR RACK1 RASA1 RELA RPL11 SH2B1 SHC1 SIRPA SOCS1 SOCS2 SOCS3 SRC STAT3 STYX THRSP TTYH2 UBC VAV3 VPS45 YWHAB YWHAE YWHAG YWHAZ
Entrez ID 4734 3480
HPRD ID 03786 00932
Ensembl ID ENSG00000069869 ENSG00000140443
Uniprot IDs P46934 C9J5X1 P08069
PDB IDs 2KPZ 2KQ0 2M3O 2XBB 2XBF 3B7Y 4BBN 4BE8 4N7F 4N7H 5AHT 5C7J 5C91 1IGR 1JQH 1K3A 1M7N 1P4O 2OJ9 2ZM3 3D94 3F5P 3I81 3LVP 3LW0 3NW5 3NW6 3NW7 3O23 3QQU 4D2R 4XSS 5FXQ 5FXR 5FXS 5HZN 5U8Q 5U8R 6JK8 6VWG 6VWH 6VWI 6VWJ
Enriched GO Terms of Interacting Partners?
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