ATM and XPA

  • Number of citations of the paper that reports this interaction (PubMedID 16540648)
  • 44
  • Data Source:
  • BioGRID (enzymatic study)
  • HPRD (in vitro)

ATM

XPA

Description ATM serine/threonine kinase XPA, DNA damage recognition and repair factor
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Hypothyroidism ( 27182965)
  • Obesity-related traits ( 23251661)
  • Serum thyroid-stimulating hormone levels ( 24852370)
  • Thyroid cancer (Papillary, radiation-related) ( 20350937)
Interacting Genes 109 interacting genes: AATF ABL1 ACTL6B AP1B1 AP2B1 AP3B1 AP3B2 ARHGAP20 ATR BCAS3 BCL10 BCO2 BRCA1 BRCA2 CD9 CDC6 CDKN2C CHD4 CHEK1 CHEK2 COPS5 CREB1 CRX CRYAB CSNK1D CXXC5 DAXX DCAF1 DCLRE1C DDX1 DYRK2 E2F1 E4F1 EEF1E1 EIF3E EIF4EBP1 ERRFI1 ESRRG EXO1 FANCD2 FECH FOXO3 H2AX HIF1A HINT1 HSPA8 HSPB2 IL24 KAT5 KAT8 LIG4 MAP1S MCM2 MCPH1 MDC1 MDM2 MDM4 MRE11 MT-ND4 MTA3 NBN NFE2L2 NR4A1 NREP NSD3 OSGIN1 PAN2 PARP1 PEX5 PGR POLR2A POLR2F PPP2R5C PRKDC PTCH1 PTS RAD17 RAD51 RAD9A RANBP9 RASSF1 RBBP8 RHEB RNF20 RNF40 RPA1 RPA2 SMC1A SPSB1 STK11 TCL1A TELO2 TERF1 TERF2 TFF1 TIPARP TOP1 TOPBP1 TP53 TP53BP1 TRAF6 TREX1 TRIM29 UCHL3 WRN XPA XRCC5 ZEB1 ZNF821 52 interacting genes: AP2M1 ARID3A ATM ATR AURKA BMPR1A BUB1 DDB1 DDB2 DLC1 DVL3 ERCC1 ERCC4 ERCC6 FBXW7 GPN1 GTF2E2 GTF2H1 HERC2 MEOX2 MLH1 MLH3 MSH2 MSH3 MUTYH NDEL1 NRAS PCNA PDGFRL PICK1 PMS2 POLR1C PRDM16 PRKDC PSMB1 RASSF1 RB1 RHOU RPA1 RPA2 RPA4 SKIL SMAD2 SNPH SRC STK11 TBC1D7 TRIM27 VPS26C XAB2 XPC ZNF655
Entrez ID 472 7507
HPRD ID 06347 02045
Ensembl ID ENSG00000149311 ENSG00000136936
Uniprot IDs A0A024R3C7 Q13315 P23025
PDB IDs 5NP0 5NP1 6HKA 6K9K 6K9L 1D4U 1XPA 2JNW 6J44 6LAE 6RO4
Enriched GO Terms of Interacting Partners?
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