NDUFB9 and TNIP2

		NDUFB9	TNIP2
Description		NADH:ubiquinone oxidoreductase subunit B9	TNFAIP3 interacting protein 2
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I	Nucleoplasm Cytosol
	Molecular Function	Protein Binding NADH Dehydrogenase (ubiquinone) Activity	Protein Binding Protein Kinase Binding Polyubiquitin Modification-dependent Protein Binding Metal Ion Binding K63-linked Polyubiquitin Modification-dependent Protein Binding
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Sensory Perception Of Sound Mitochondrial Respiratory Chain Complex I Assembly	Regulation Of Transcription By RNA Polymerase II Apoptotic Process Inflammatory Response CD40 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Positive Regulation Of Macrophage Activation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Transcription By RNA Polymerase II Protein Stabilization Positive Regulation Of B Cell Activation Interleukin-1-mediated Signaling Pathway Cellular Response To Lipopolysaccharide Negative Regulation Of Endothelial Cell Apoptotic Process
Pathways		Respiratory electron transport Complex I biogenesis	MAP3K8 (TPL2)-dependent MAPK1/3 activation Ovarian tumor domain proteases
Drugs		NADH
Diseases
GWAS			Extrinsic epigenetic age acceleration ( 29374233) Multiple sclerosis ( 31604244) Systemic lupus erythematosus ( 33536424)
Interacting Genes		20 interacting genes: DRC7 ELP1 EYA1 FEZ1 GDF9 HAP1 IMMT MAGEA11 MEF2A MYCBP2 OR2D2 PRDM14 PRPF31 PSMB9 RAD54B RBBP6 SH3GL3 TNIP2 UBC XRN1	29 interacting genes: APP CACNA1C CDKN1A CLK1 EP300 FBXO25 FLNA FXR2 GCH1 IKBKG MAP3K8 MAPK1 MKNK1 NCOR2 NDUFB9 NFKB1 NFKB2 PSMD9 REL RELA SHANK3 SMARCD1 SMURF1 SRPK2 STK11 TEK TNFAIP3 TSG101 UBC
Entrez ID		4715	79155
HPRD ID		03264	18207
Ensembl ID		ENSG00000147684	ENSG00000168884
Uniprot IDs		E9PH64 Q9Y6M9	D6RGJ2 Q8NFZ5
PDB IDs		5XTC 5XTD 5XTH 5XTI	5H07
Enriched GO Terms of Interacting Partners?
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