MYOD1 and ID4

Number of citations of the paper that reports this interaction (PubMedID 11756408)
33

Data Source:
HPRD (two hybrid)

		MYOD1	ID4
Description		myogenic differentiation 1	inhibitor of DNA binding 4, HLH protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Euchromatin Nucleus Nucleoplasm Transcription Regulator Complex Myofibril	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding Nuclear Receptor Binding Chromatin DNA Binding Ubiquitin Protein Ligase Binding Protein Homodimerization Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding E-box Binding Sequence-specific Double-stranded DNA Binding Promoter-specific Chromatin Binding	Protein Binding Protein Dimerization Activity Transcription Regulator Activity Transcription Regulator Inhibitor Activity
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Transcription By RNA Polymerase II Protein Phosphorylation Muscle Organ Development Myoblast Fate Determination Skeletal Muscle Tissue Development Myoblast Fusion Cellular Response To Starvation Myotube Cell Development Myotube Differentiation Involved In Skeletal Muscle Regeneration Negative Regulation Of Chromatin Binding Skeletal Muscle Cell Differentiation Muscle Cell Fate Commitment Positive Regulation Of Skeletal Muscle Tissue Regeneration Regulation Of RNA Splicing Skeletal Muscle Fiber Adaptation Histone H3 Acetylation Histone H4 Acetylation Positive Regulation Of Myoblast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Skeletal Muscle Fiber Development Positive Regulation Of Skeletal Muscle Fiber Development Positive Regulation Of Binding Positive Regulation Of Muscle Cell Differentiation Cellular Response To Tumor Necrosis Factor Cellular Response To Glucocorticoid Stimulus Cellular Response To Estradiol Stimulus Cellular Response To Oxygen Levels Positive Regulation Of Myoblast Fusion Positive Regulation Of SnRNA Transcription By RNA Polymerase II Negative Regulation Of Myoblast Proliferation	Negative Regulation Of Transcription By RNA Polymerase II Cell Differentiation Circadian Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated
Pathways		Myogenesis Myogenesis	NGF-stimulated transcription
Drugs
Diseases
GWAS		Body mass index ( 26426971) Hodgkin's lymphoma ( 34216518) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917)	Age at first birth ( 34211149) Age at voice drop ( 27182965) Age-related cognitive decline (attention/processing speed) (slope of z-scores) ( 30954325) Anthropometric traits ( 30166351) Anthropometric traits (multi-trait analysis) ( 30166351) Automobile speeding propensity ( 30643258) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Chronic obstructive pulmonary disease ( 30804561) Chronotype ( 30696823) Deep ovarian and/or rectovaginal disease with dense adhesions ( 28333195) Endometriosis ( 23472165 28333195 28537267) Free thyroxine concentration ( 30367059) Height ( 28552196 20881960) Hip circumference adjusted for BMI ( 34021172) Loneliness (multivariate analysis) ( 27629369) Response to statin therapy ( 20339536) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		67 interacting genes: AP1M1 ASCL3 BHLHA15 BHLHE40 BHLHE41 C2orf88 CALM1 CALM2 CALM3 CARM1 CDC34 CDK2 CDK4 CDKN1C CIB2 CREBBP CSRP3 ELSPBP1 EP300 EXOC3L1 FBXO32 FIGLA HAND1 HDAC1 HEY1 HSP90AA1 ID1 ID2 ID3 ID4 IFRD1 IGFN1 JUN KAT2B KAT5 KPNA3 LMO4 MDFI MEF2A MEF2C MOS MYOCD NCOR1 NCOR2 NR2F2 PHB2 POLR2G PRKCA PRMT5 PSMD4 PSME2 RB1 RORA RUNX1 RXRA SETD3 SMAD3 SMAD4 SMAD7 SP1 SRF STAT3 SUV39H1 TCF21 TCF3 TCF4 TWIST1	5 interacting genes: GRIN2A HES1 ID3 MYOD1 TCF4
Entrez ID		4654	3400
HPRD ID		01166	08995
Ensembl ID		ENSG00000129152	ENSG00000172201
Uniprot IDs		P15172	P47928
PDB IDs
Enriched GO Terms of Interacting Partners?
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