MYO1C and MYH10

Number of citations of the paper that reports this interaction (PubMedID 22939629)
326

Data Source:
BioGRID (biochemical)

		MYO1C	MYH10
Description		myosin IC	myosin heavy chain 10
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GO Annotations	Cellular Component	Stress Fiber Nuclear Pore Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Microvillus Brush Border Basal Plasma Membrane Actin Cytoskeleton Membrane Lateral Plasma Membrane Unconventional Myosin Complex Nuclear Body Cytoplasmic Vesicle Membrane Filamentous Actin Vesicle Ruffle Membrane Membrane Raft Phagocytic Vesicle Stereocilium Membrane Extracellular Exosome	Stress Fiber Nucleus Cytoplasm Cytosol Polysome Cell Cortex Myosin Complex Myosin II Complex Lamellipodium Midbody Cleavage Furrow Actomyosin Extracellular Exosome Myosin II Filament
	Molecular Function	Microfilament Motor Activity Signaling Receptor Binding Protein Binding Calmodulin Binding ATP Binding Protein C-terminus Binding Small GTPase Binding Actin Filament Binding	Microfilament Motor Activity Actin Binding Protein Binding Calmodulin Binding ATP Binding RNA Stem-loop Binding ADP Binding MRNA 5'-UTR Binding Actin Filament Binding
	Biological Process	Protein Targeting Protein Targeting To Membrane Actin Filament Organization Vesicle Transport Along Actin Filament Positive Regulation Of Cell Migration Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway MRNA Transport Cellular Response To Interferon-gamma Positive Regulation Of Protein Targeting To Membrane Positive Regulation Of Cellular Response To Insulin Stimulus Positive Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Regulation Of Bicellular Tight Junction Assembly	Mitotic Cytokinesis Cell Adhesion Regulation Of Cell Shape Actin Filament-based Movement Actomyosin Structure Organization Positive Regulation Of Protein Secretion Modification Of Postsynaptic Actin Cytoskeleton
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Regulation of actin dynamics for phagocytic cup formation Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea FCGR3A-mediated phagocytosis	EPHA-mediated growth cone collapse Sema4D induced cell migration and growth-cone collapse RHO GTPases activate PKNs RHO GTPases activate CIT RHO GTPases Activate ROCKs RHO GTPases activate PAKs RHO GTPases activate PAKs
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Atrial fibrillation ( 30061737) Mean platelet volume ( 32888494) Neutrophil count ( 32888494) Pulse pressure ( 30578418) White blood cell count ( 32888494)	Type 2 diabetes ( 30130595)
Interacting Genes		7 interacting genes: BAZ1B CBL CDC42 KHDRBS1 MYH10 PTEN RRN3	20 interacting genes: APC BCAP31 DUX4 ECPAS EIF4A1 FXR1 FXR2 GPS2 ITGAE MYH9 MYO1C PBX1 PTEN S100A4 SERPINF2 UBL4A XRN1 YWHAE YWHAG ZNF512B
Entrez ID		4641	4628
HPRD ID		09411	01178
Ensembl ID		ENSG00000197879	ENSG00000133026
Uniprot IDs		O00159	G1UI33 P35580
PDB IDs		4BYF	4PD3
Enriched GO Terms of Interacting Partners?
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