SERPINC1 and KLK1

Number of citations of the paper that reports this interaction (PubMedID 3643793)
29

Data Source:
BioGRID (pull down)

		SERPINC1	KLK1
Description		serpin family C member 1	kallikrein 1
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Plasma Membrane Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle	Nucleus Secretory Granule Extracellular Exosome
	Molecular Function	Protease Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding Heparin Binding Identical Protein Binding	Serine-type Endopeptidase Activity
	Biological Process	Acute Inflammatory Response To Antigenic Stimulus Response To Nutrient Lactation Blood Coagulation Negative Regulation Of Endopeptidase Activity Regulation Of Blood Coagulation, Intrinsic Pathway	Regulation Of Systemic Arterial Blood Pressure Zymogen Activation
Pathways		Intrinsic Pathway of Fibrin Clot Formation Common Pathway of Fibrin Clot Formation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Drugs		Ardeparin Fondaparinux Heparin Enoxaparin N-Formylmethionine SR-123781A Sulodexide Danaparoid Dalteparin Tinzaparin Nadroparin Copper Protamine sulfate Bemiparin Antithrombin III human	Aluminium Benzamidine Lanoteplase Aprotinin Aniline Nafamostat Aluminium phosphate Aluminum acetate
Diseases
GWAS		Experiencing mood swings ( 29500382) Heel bone mineral density ( 30598549)	Dental caries (decayed, missing and filled tooth surfaces) ( 31533690)
Interacting Genes		14 interacting genes: ATP1B1 CHML CREG1 F2 FMO3 HSP90AA1 KLK1 KLK2 KLK6 MRPS14 PIGC PLG QSOX1 SDC2	8 interacting genes: A2M ITIH4 KNG1 PROC SERPINA1 SERPINA4 SERPINA5 SERPINC1
Entrez ID		462	3816
HPRD ID		00122	01003
Ensembl ID		ENSG00000117601	ENSG00000167748
Uniprot IDs		A0A024R944 P01008	A0A1L2BPJ2 A0A1R3UCD2 P06870
PDB IDs		1ANT 1ATH 1AZX 1BR8 1DZG 1DZH 1E03 1E04 1E05 1JVQ 1LK6 1NQ9 1OYH 1R1L 1SR5 1T1F 1TB6 2ANT 2B4X 2B5T 2BEH 2GD4 2HIJ 2ZNH 3EVJ 3KCG 4EB1	1SPJ
Enriched GO Terms of Interacting Partners?
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