MYD88 and IRAK4

  • Number of citations of the paper that reports this interaction (PubMedID 11960013)
  • 168
  • Data Source:
  • HPRD (in vitro, in vivo)

MYD88

IRAK4

Description MYD88 innate immune signal transduction adaptor interleukin 1 receptor associated kinase 4
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Gut microbiota (bacterial taxa) ( 27723756)
  • Mean corpuscular hemoglobin concentration ( 29403010)
  • Immune reponse to smallpox (secreted TNF-alpha) ( 22610502)
  • Inflammatory bowel disease ( 27569725)
Interacting Genes 44 interacting genes: BTK CD93 CISH FADD FLII IKBKG IL1R1 IL1RAP IL1RL1 IRAK1 IRAK2 IRAK3 IRAK4 IRF4 IRF5 IRF7 MAL MBIP MDM2 NTAQ1 PELI2 PFKL POLR1C PRDX1 RAC1 RNF152 RNF4 SARM1 SIAH2 SMAD3 SPOP SPOPL STAP2 TIRAP TLR10 TLR2 TLR3 TLR4 TLR5 TLR7 TLR8 TXN USP7 ZNF35 23 interacting genes: ARNT EIF4EBP1 ERBB3 H1-1 H1-2 H1-3 H1-4 H1-5 H1-6 IKBKG IL36RN IRAK1 MBP MYD88 PELI1 PELI2 PELI3 TBPL1 TICAM2 TIRAP TRAF6 TRIM7 ZNF597
Entrez ID 4615 51135
HPRD ID 03703 06051
Ensembl ID ENSG00000172936 ENSG00000198001
Uniprot IDs A0A0A0MSI9 A0A3B3ITY3 A0A3F2YP85 Q99836 B2RAP9 B4E359 Q69FE3 Q9NWZ3
PDB IDs 2JS7 2Z5V 3MOP 4DOM 4EO7 6I3N 2NRU 2NRY 2O8Y 2OIB 2OIC 2OID 3MOP 4RMZ 4U97 4U9A 4XS2 4Y73 4YO6 4YP8 4ZTL 4ZTM 4ZTN 5K72 5K75 5K76 5K7G 5K7I 5KX7 5KX8 5T1S 5T1T 5UIQ 5UIR 5UIS 5UIT 5UIU 5W84 5W85 6EG9 6EGA 6EGD 6EGE 6EGF 6F3D 6F3E 6F3G 6F3I 6LXY 6MOM 6N8G 6O8U 6O94 6O95 6O9D 6RFI 6RFJ 6THW 6THX 6THZ 6TI8 6TIA 6UYA 6VQL 7C2V 7C2W
Enriched GO Terms of Interacting Partners?
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