MYCL and MXD1

Number of citations of the paper that reports this interaction (PubMedID 11602341)
68

Data Source:
HPRD (in vivo, in vitro)

		MYCL	MXD1
Description		MYCL proto-oncogene, bHLH transcription factor	MAX dimerization protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleoplasm Chromosome	Chromatin Nucleoplasm Mitochondrion Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Dimerization Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Protein Dimerization Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Regulation Of Inner Ear Auditory Receptor Cell Differentiation	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS			Carotid plaque burden (smoking interaction) ( 24954085) High light scatter reticulocyte count ( 32888494 27863252) Mean platelet volume ( 32888494 27863252) Platelet count ( 32888494 27863252) Red cell distribution width ( 28957414) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		6 interacting genes: CATSPER1 CCNK MAX MXD1 OTUD6A PRKAA2	20 interacting genes: AKT1 APP CD2 HDAC1 HDAC2 MAX MLX MOGS MYC MYCL MYCN PML PRAM1 REL RPS6KA1 RPS6KB1 SAP30 SIN3A SIN3B SMC3
Entrez ID		4610	4084
HPRD ID		01279	02487
Ensembl ID		ENSG00000116990	ENSG00000059728
Uniprot IDs		P12524	B7ZLI7 Q05195
PDB IDs			1E91 1G1E 1NLW 1PD7 1S5Q
Enriched GO Terms of Interacting Partners?
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