GET3 and WFDC3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

		GET3	WFDC3
Description		guided entry of tail-anchored proteins factor 3, ATPase	WAP four-disulfide core domain 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm GET Complex Extracellular Exosome	Extracellular Space
	Molecular Function	Protein Binding ATP Binding Arsenite Transmembrane Transporter Activity Hydrolase Activity ATP Hydrolysis Activity Metal Ion Binding	Serine-type Endopeptidase Inhibitor Activity Protein Binding
	Biological Process	Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Arsenite Transport Tail-anchored Membrane Protein Insertion Into ER Membrane	Negative Regulation Of Endopeptidase Activity Antibacterial Humoral Response Innate Immune Response
Pathways		Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs		ATP
Diseases
GWAS
Interacting Genes		41 interacting genes: AGR2 APLN ASPH CACNA1A CAMLG CREB3L4 EMSY FAM209A FKBP7 GET4 GOLM1 GPX7 GPX8 HILPDA IGFBP6 KCNE4 KCNE5 LDLRAD4 PDIA6 PEX14 PFDN1 PGRMC1 PGRMC2 PRB3 PRR4 RHEX SEC61A1 SEC61B SMIM19 SPP1 STATH STX5 SYPL2 TK1 TMEM154 TMEM51 TMX1 TTR VAMP2 VWC2 WFDC3	2 interacting genes: GET3 LCE1F
Entrez ID		439	140686
HPRD ID		03555	15676
Ensembl ID		ENSG00000198356	ENSG00000124116
Uniprot IDs		O43681	Q8IUB2
PDB IDs		6SO5
Enriched GO Terms of Interacting Partners?
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