MME and NPPA

  • Number of citations of the paper that reports this interaction (PubMedID 2972276)
  • 18
  • Data Source:
  • BioGRID (enzymatic study)
  • HPRD (in vitro)

MME

NPPA

Description membrane metalloendopeptidase natriuretic peptide A
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Diastolic blood pressure ( 27841878)
  • Primary sclerosing cholangitis ( 27992413)
  • Systolic blood pressure ( 27841878)
  • Triglyceride levels in HIV infection ( 33109212)
  • Vaginal microbiome composition (Shannon diversity index) ( 32723796)
  • Atrial fibrillation ( 19597492)
  • Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Midregional pro atrial natriuretic peptide levels ( 29237677)
  • Psoriasis ( 25854761)
  • Pulse pressure ( 30578418)
  • Systolic blood pressure ( 19430483 30578418)
  • Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Tuberculosis ( 29036319)
Interacting Genes 18 interacting genes: ADCYAP1 ADM AGT CSNK2A1 CSNK2B EDN1 EDN2 EZR GAST LYN NDRG1 NPPA NPPC PIK3CB PIK3R1 PTEN SHC1 VIP 15 interacting genes: EPB41 ESR1 HNF4A HSF2BP KAZN MAGEA12 MME NPR1 NPR2 NPR3 NR5A2 RORB UBQLN1 UBQLN2 UBQLN4
Entrez ID 4311 4878
HPRD ID 00392 00164
Ensembl ID ENSG00000196549 ENSG00000175206
Uniprot IDs P08473 P01160
PDB IDs 1DL9 1DMT 1QVD 1R1H 1R1I 1R1J 1Y8J 2QPJ 2YB9 4CTH 5JMY 6GID 6SH1 6SH2 6SUK 6SVY 6THP 6XVP 1ANP 1YK0 3N57
Enriched GO Terms of Interacting Partners?
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