CXCL9 and CXCL12

  • Number of citations of the paper that reports this interaction (PubMedID 28381538)
  • 37

CXCL9

CXCL12

Description C-X-C motif chemokine ligand 9 C-X-C motif chemokine ligand 12
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood protein levels ( 28240269)
  • Hippocampal volume ( 29274321)
  • Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952)
  • Anti-drug antibodies in autoimmune disease (time to event) ( 33125391)
  • Blood protein levels ( 30072576)
  • Body mass index ( 25760438)
  • Coronary artery disease ( 32469254 26708285 24262325 26343387)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Coronary heart disease ( 17634449 21378990)
  • Diastolic blood pressure ( 27841878)
  • Eosinophil counts ( 32888494)
  • Eosinophil percentage of white cells ( 32888494)
  • Granulocyte count ( 27863252)
  • Hematocrit ( 32888494)
  • Hemoglobin ( 32888494)
  • Left superior temporal gyrus thickness (schizophrenia interaction) ( 26249676)
  • Lymphocyte counts ( 32888494)
  • Monocyte count ( 32888494 27863252)
  • Myeloid white cell count ( 27863252)
  • Myocardial infarction ( 33532862 26343387)
  • Myocardial infarction (early onset) ( 19198609)
  • Neutrophil count ( 32888494 27863252)
  • QT interval (ambient particulate matter interaction) ( 28749367)
  • Red blood cell count ( 32888494)
  • Resistance to Mycobacterium tuberculosis in HIV-positive individuals measured by a negative tuberculin skin test (continuous) ( 28628665)
  • Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy) ( 24554482)
  • Schizophrenia ( 23212062)
  • Smoking initiation (ever regular vs never regular) ( 31089300)
  • Sum basophil neutrophil counts ( 27863252)
  • Sum neutrophil eosinophil counts ( 27863252)
  • White blood cell count ( 32888494 27863252)
Interacting Genes 76 interacting genes: AMIGO1 AQP6 ATP1B4 BMF BSCL2 BTNL9 C16orf92 CCL11 CCL13 CCL2 CCL21 CCL26 CCL28 CCL5 CCR3 CD33 CHODL CLDN2 CLDN5 CLDN7 CLEC17A CLEC2D CLEC4E CLEC7A CXCL10 CXCL11 CXCL12 CXCL14 CXCL17 CXCL2 CXCR3 DPP4 EPGN EREG FBXO7 FCGR2A FFAR2 FNDC9 FUT7 GJB1 GORAB GPR42 IFNGR2 ITM2C KASH5 KIR2DL3 LDLRAD1 LEUTX LRRC25 LSMEM2 MR1 MTIF3 MUC1 NEMP1 PAX8 PF4 PPBP PTPN5 RHCG SFTPC SLC10A1 SLC39A1 SSMEM1 SUSD3 SYNE4 TM4SF18 TMED5 TMEM106C TMEM234 TMEM237 TMEM31 TMPRSS2 TNFSF14 TNFSF8 TSPAN18 XCL1 32 interacting genes: CCL11 CCL13 CCL20 CCL21 CCL25 CCL26 CCL28 CCL5 CD4 CTSG CXCL10 CXCL11 CXCL14 CXCL17 CXCL2 CXCL6 CXCL9 CXCR4 DAZAP2 DPP4 ELANE FBXO7 FN1 MMP2 NIF3L1 PF4 PF4V1 PPBP RPS6KA1 VCAN XCL1 XCL2
Entrez ID 4283 6387
HPRD ID 03416 02904
Ensembl ID ENSG00000138755 ENSG00000107562
Uniprot IDs Q07325 P48061
PDB IDs 1A15 1QG7 1SDF 1VMC 2J7Z 2K01 2K03 2K04 2K05 2KEC 2KED 2KEE 2KOL 2N55 2NWG 2SDF 3GV3 3HP3 4LMQ 4UAI 6SHR
Enriched GO Terms of Interacting Partners?
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