MGAT3 and UBAC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MGAT3	UBAC1
Description		beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	UBA domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Integral Component Of Membrane	Golgi Apparatus Cytosol Plasma Membrane Extracellular Exosome
	Molecular Function	Beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase Activity Protein Binding Glycosyltransferase Activity	Protein Binding
	Biological Process	N-acetylglucosamine Metabolic Process Protein N-linked Glycosylation Protein Localization Regulation Of Cell Migration Cellular Response To Oxidative Stress Amyloid-beta Metabolic Process Cognition Positive Regulation Of Protein Localization To Early Endosome Negative Regulation Of Lysosomal Protein Catabolic Process	Protein Ubiquitination
Pathways		Reactions specific to the hybrid N-glycan synthesis pathway	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		General cognitive ability ( 29844566) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis) ( 28878392) IgG digalactosylation phenotypes (multivariate analysis) ( 28878392) IgG disialylation phenotypes (multivariate analysis) ( 28878392) IgG fucosylation phenotypes (multivariate analysis) ( 28878392) IgG galactosylation phenotypes (multivariate analysis) ( 28878392) IgG glycosylation ( 23382691) IgG monogalactosylation phenotypes (multivariate analysis) ( 28878392) IgG N-glycosylation phenotypes (multivariate analysis) ( 28878392 32128391) IgG sialylation phenotypes (multivariate analysis) ( 28878392) Post bronchodilator FEV1 ( 26634245) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Schizophrenia ( 29483656) Sleep duration (short sleep) ( 30846698)	Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Lung adenocarcinoma (survival time) in never smokers ( 32699080) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Ulcerative colitis ( 28067908)
Interacting Genes		2 interacting genes: HSPD1 UBAC1	36 interacting genes: AIRE APP ARRDC3 CARD14 CCDC138 CDKN1B CPSF6 CSNK2A1 DAZAP2 DVL2 FAM168A HOXA2 HTT IGFBP6 LAPTM5 MAP3K1 MCM10 MGAT3 NEDD4L PLAAT2 PLEKHB2 PMPCA POU6F2 PPP1CB RNF11 RNF123 RNF216 SMURF1 SPART TRIM2 TRIM39 UBB UBC UBQLN2 ZDHHC17 ZG16B
Entrez ID		4248	10422
HPRD ID		07058	12170
Ensembl ID		ENSG00000128268	ENSG00000130560
Uniprot IDs		Q09327	A0A140VK64 Q9BSL1
PDB IDs			2DAI
Enriched GO Terms of Interacting Partners?
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