MFGE8 and TM6SF1

		MFGE8	TM6SF1
Description		milk fat globule EGF and factor V/VIII domain containing	transmembrane 6 superfamily member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Acrosomal Membrane Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen External Side Of Plasma Membrane Membrane Extrinsic Component Of Plasma Membrane Collagen-containing Extracellular Matrix Extracellular Exosome Extracellular Vesicle	Lysosomal Membrane Integral Component Of Membrane
	Molecular Function	Phosphatidylserine Binding Integrin Binding Extracellular Matrix Structural Constituent Phosphatidylethanolamine Binding	Molecular_function
	Biological Process	Angiogenesis Phagocytosis, Recognition Phagocytosis, Engulfment Cell Adhesion Single Fertilization Apoptotic Cell Clearance Positive Regulation Of Phagocytosis	Biological_process
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation Amyloid fiber formation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Coronary artery disease ( 32469254 26343387 33020668) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Liver enzyme levels (alkaline phosphatase) ( 33972514) Major depressive disorder x sex interaction ( 34099189) Pulse pressure ( 27841878) Serum alkaline phosphatase levels ( 33547301) Squamous cell lung carcinoma ( 28604730)	Diastolic blood pressure ( 27841878) Lymphocyte counts ( 32888494)
Interacting Genes		7 interacting genes: LOXL1 MRPL46 MRPS11 PRLR PSTPIP1 TM6SF1 TRIP13	3 interacting genes: MFF MFGE8 PEX5
Entrez ID		4240	53346
HPRD ID		03789	08411
Ensembl ID		ENSG00000140545	ENSG00000136404
Uniprot IDs		B3KTQ2 B4E396 Q08431	Q6P4D7 Q9BZW5
PDB IDs
Enriched GO Terms of Interacting Partners?
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