MAGEA3 and ACOT7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MAGEA3	ACOT7
Description		MAGE family member A3	acyl-CoA thioesterase 7
Image
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum	Nucleoplasm Mitochondrion Cytosol Extracellular Exosome
	Molecular Function	Protein Binding Histone Deacetylase Binding Caspase Binding	Fatty-acyl-CoA Binding Protein Binding Palmitoyl-CoA Hydrolase Activity Long-chain Fatty Acyl-CoA Binding Protein Homodimerization Activity Acyl-CoA Hydrolase Activity Carboxylic Ester Hydrolase Activity Myristoyl-CoA Hydrolase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Autophagy Negative Regulation Of Protein Processing Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway	Fatty Acid Metabolic Process Acyl-CoA Metabolic Process Coenzyme A Biosynthetic Process Medium-chain Fatty-acyl-CoA Catabolic Process Long-chain Fatty-acyl-CoA Catabolic Process Medium-chain Fatty Acid Biosynthetic Process Palmitic Acid Biosynthetic Process
Pathways			Mitochondrial Fatty Acid Beta-Oxidation
Drugs
Diseases
GWAS			Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Body shape index ( 34021172) HDL cholesterol levels in HIV infection ( 33109212) Metabolite levels ( 31628463) QT interval ( 19305408) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172)
Interacting Genes		16 interacting genes: ACOT7 BCL7B C17orf49 CINP DNM1L ENOX2 EXOC5 HLA-DRB1 HTT IQSEC1 KIF27 LSM2 PCYT1A RUSC1 S100A9 STAMBPL1	26 interacting genes: ACOT12 ATXN1 ATXN1L BAG4 CAMK2B CDC42 CRYAB DAZAP2 DLC1 ENKD1 FXR1 HOXA1 LMNA MAGEA3 MAGEA6 NCOA5 POT1 POU6F1 SPATC1L TERF1 THAP1 TINF2 UBQLN1 UBQLN2 UBXN1 ZNF438
Entrez ID		4102	11332
HPRD ID		02166	12517
Ensembl ID		ENSG00000221867	ENSG00000097021
Uniprot IDs		P43357	O00154
PDB IDs		1QEW 4V0P 5BRZ	2QQ2
Enriched GO Terms of Interacting Partners?
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