SH2D1A and SLAMF7

Number of citations of the paper that reports this interaction (PubMedID 12621057)
10

Data Source:
HPRD (two hybrid)

		SH2D1A	SLAMF7
Description		SH2 domain containing 1A	SLAM family member 7
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	Identical Protein Binding
	Biological Process	Adaptive Immune Response Humoral Immune Response Cellular Defense Response Cell-cell Signaling Innate Immune Response Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response Negative Regulation Of T Cell Receptor Signaling Pathway	Adaptive Immune Response Cell Adhesion Natural Killer Cell Activation T Cell Activation Natural Killer Cell Mediated Cytotoxicity
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs			Elotuzumab
Diseases
GWAS			Blood protein levels ( 30072576 29875488 28240269) IgM levels ( 28628107) Inflammatory bowel disease ( 23128233) Microalbuminuria ( 26631737) Multiple sclerosis ( 24076602)
Interacting Genes		33 interacting genes: AR ARHGEF6 ARHGEF7 ATF3 CCDC74A CD244 CD84 DOK1 EGFR ERBB2 ERBB3 ERBB4 FYB1 FYN GRB2 KIT LCK LETMD1 LHX3 LHX4 LY9 MAPK11 MAPK14 MET NCK1 NGEF OLIG1 PTK2 SLAMF1 SLAMF6 SLAMF7 TNK2 ZNHIT1	11 interacting genes: ADRA2A API5 CLK3 MAK PANK1 PITX2 SH2D1A SVIL THRSP TMOD4 TRIB2
Entrez ID		4068	57823
HPRD ID		02390	09432
Ensembl ID		ENSG00000183918	ENSG00000026751
Uniprot IDs		O60880	B4DVL7 B4DW98 Q9NQ25
PDB IDs		1D1Z 1D4T 1D4W 1KA6 1KA7 1M27
Enriched GO Terms of Interacting Partners?
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