LYN and ARFGEF1

LYN

ARFGEF1

Description LYN proto-oncogene, Src family tyrosine kinase ADP ribosylation factor guanine nucleotide exchange factor 1
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Chronic central serous retinopathy ( 30073298)
  • Hearing function ( 25060954)
  • Hip circumference adjusted for BMI ( 28552196)
Interacting Genes 137 interacting genes: ACTB ADAM15 AGXT AR ARFGEF1 BANK1 BCAR1 BTK CASP3 CASP7 CASP9 CBL CBLC CD19 CD22 CD36 CD72 CD79A CD79B CDK1 CDK2 CDKN1B CHST15 CLCF1 COASY CREBBP CRH CRKL CSF1R CSF2RA CSF2RB CSF3R CSK CSNK2B CTLA4 DAPP1 DLG4 DOK1 DOK2 DOK3 EGFR EPOR ERBB3 ERBB4 EVL FASLG FCAR FCER1G FCGR2A FCGR2B FOLR1 GAB2 GAB3 GP6 GRIA3 HCLS1 HNRNPK IGHA1 IL1B IL2RB IL7 IL7R INPP5D ITPR1 JAK2 KHDRBS1 KIT KLHL41 LCP2 LIME1 MAP4K1 MAPK3 MATK MET MME MS4A1 MS4A2 MUC1 NDFIP2 NEDD9 NEK7 NMT1 NPHS1 PAG1 PAK2 PDCD4 PDE4A PDE4D PECAM1 PIK3CG PILRB PLCG1 PLCG2 PNMA2 PPP1R15A PPP1R8 PRAM1 PRKCD PRKCQ PRKDC PRRG4 PTK2 PTK2B PTPN6 PTPRC RASA1 RGS16 RPL10 RPS6KB1 RPS6KB2 SGK3 SH2B2 SHC1 SKAP1 SKAP2 SLC4A1 SNCA SOCS1 SPHK1 SPHK2 SRC STAT3 SYK TEC TERF1 TNF TRAT1 TRIM28 TRIM55 TRIM63 TRIP10 TRPA1 TRPV4 TYK2 UBB UHRF2 UNC119 6 interacting genes: ARFGEF2 CTNNB1 DPY30 FKBP2 LYN MYO9B
Entrez ID 4067 10565
HPRD ID 01301 09163
Ensembl ID ENSG00000254087 ENSG00000066777
Uniprot IDs A8K379 P07948 Q6NUK7 A0A024R7X0 Q9Y6D6
PDB IDs 1W1F 1WA7 3A4O 5XY1 6NMW 3LTL 5EE5 5J5C
Enriched GO Terms of Interacting Partners?
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