LTBP3 and MBD1

Number of citations of the paper that reports this interaction (PubMedID 21653829)
98

Data Source:
BioGRID (two hybrid)

		LTBP3	MBD1
Description		latent transforming growth factor beta binding protein 3	methyl-CpG binding domain protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen-containing Extracellular Matrix Extracellular Exosome	Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Nuclear Speck
	Molecular Function	Calcium Ion Binding Protein Binding Transforming Growth Factor Beta Binding	DNA Binding Chromatin Binding Protein Binding Zinc Ion Binding Methyl-CpG Binding Double-stranded Methylated DNA Binding Unmethylated CpG Binding
	Biological Process	Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Bone Mineralization Negative Regulation Of Chondrocyte Differentiation Transforming Growth Factor Beta Activation Positive Regulation Of Bone Resorption Bone Remodeling Elastic Fiber Assembly Bone Morphogenesis Lung Saccule Development Positive Regulation Of Mesenchymal Stem Cell Proliferation Positive Regulation Of Mesenchymal Stem Cell Differentiation	Transcription By RNA Polymerase II Heart Development Aging Response To Xenobiotic Stimulus Negative Regulation Of Gene Expression Neuron Differentiation Response To Nutrient Levels Response To Estradiol Response To Cocaine Regulation Of DNA Methylation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Astrocyte Differentiation
Pathways		Molecules associated with elastic fibres	SUMOylation of transcription cofactors
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Eosinophil counts ( 32888494) Heel bone mineral density ( 30598549) Hip circumference adjusted for BMI ( 34021172) Lymphocyte counts ( 32888494) Non-alcoholic fatty liver disease histology (lobular) ( 20708005) Osteoarthritis (hip) ( 30374069) Refractive error ( 32231278) Serum alkaline phosphatase levels ( 33547301) Urate levels ( 23263486) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Chronic lymphocytic leukemia ( 28165464)
Interacting Genes		16 interacting genes: CACNA1A CCNG1 GORASP2 HBEGF HOXA1 ITGB5 MBD1 NUFIP2 PELI2 PIK3R2 PRPF40A RAC1 SHANK3 TGFB1 TGFB2 TGFB3	45 interacting genes: APP ATF7IP ATF7IP2 ATXN1L C1QBP CBX4 CBX5 CCDC136 CHAF1A COPE DVL3 ECT2 EEF1G GRN HDAC3 HIPK3 HTT JAG2 LTBP3 LTBP4 MDFI MEGF6 NELL1 NELL2 NOTCH1 NOTCH3 OASL PIAS1 PIAS2 POMGNT1 RNF2 SETDB1 SLC25A3 SMAD1 SMAD3 SMAD5 SMAD7 SMAD9 SNAPC2 SP1 SUV39H1 TENM1 TNC ZNF384 ZNF512B
Entrez ID		4054	4152
HPRD ID		03649	01133
Ensembl ID		ENSG00000168056	ENSG00000141644
Uniprot IDs		B9EG76 Q8WYU6 Q9NS15	A8K654 B4DI41 B4DUR3 Q9UIS9
PDB IDs			1D9N 1IG4 4D4W 5W9Q 6D1T
Enriched GO Terms of Interacting Partners?
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