LRP6 and ANTXR2

  • Number of citations of the paper that reports this interaction (PubMedID 16564009)
  • 54
  • Data Source:
  • HPRD (in vivo, in vitro)

LRP6

ANTXR2

Description LDL receptor related protein 6 ANTXR cell adhesion molecule 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cerebrospinal fluid t-tau levels in normal cognition ( 29274321)
  • Cerebrospinal fluid t-tau:AB1-42 ratio ( 28641921)
  • Coronary artery calcification ( 23870195)
  • Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Heel bone mineral density ( 30598549)
  • Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Tandem gait ( 26219847)
  • Adult body size ( 32376654)
  • Ankylosing spondylitis ( 21743469 20062062)
  • Bipolar disorder (inflammation and infection response interaction) ( 25781172)
  • Carotid plaque burden ( 28282560)
  • Childhood ALL/LBL (acute lymphoblastic leukemia/lymphoblastic lymphoma) treatment-related venous thromboembolism ( 32438682)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Essential hypertension (time to event) ( 32589924)
  • Hand grip strength ( 29691431)
  • Lymphocyte counts ( 32888494 27863252)
  • Lymphocyte percentage of white cells ( 32888494 27863252)
  • Myopia ( 27182965)
  • Neutrophil percentage of white cells ( 32888494 27863252)
  • Refractive error ( 32231278)
  • Response to cognitive-behavioural therapy in major depressive disorder ( 31123309)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
  • White blood cell count ( 32888494)
Interacting Genes 18 interacting genes: ANTXR1 ANTXR2 APOB ATP13A2 AXIN1 CKLF DKK1 DKK2 FZD5 FZD8 GSK3A GSK3B LRRK2 MDK SERPINF1 TLNRD1 WNT1 WNT3A 11 interacting genes: COL4A2 COL4A3 COL4A4 COL4A5 DDX10 FRAS1 LAMB1 LAMC1 LRP6 RAP1GDS1 SMAD2
Entrez ID 4040 118429
HPRD ID 04617 07452
Ensembl ID ENSG00000070018 ENSG00000163297
Uniprot IDs O75581 A4FUA5 J3KPY9 P58335 Q32Q26
PDB IDs 3S2K 3S8V 3S8Z 3S94 3SOB 3SOQ 3SOV 4A0P 4DG6 4NM5 4NM7 5AIR 5FWW 5GJE 6H15 6H16 6L6R 1SHT 1SHU 1T6B 1TZN
Enriched GO Terms of Interacting Partners?
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