LRP1 and SNX17

  • Number of citations of the paper that reports this interaction (PubMedID 12169628)
  • 48
  • Data Source:
  • HPRD (in vivo, in vitro)

LRP1

SNX17

Description LDL receptor related protein 1 sorting nexin 17
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alcohol use disorder (total score) ( 30336701)
  • Crohn's disease ( 28067908)
  • High light scatter reticulocyte count ( 27863252)
  • Inflammatory bowel disease ( 28067908)
  • LDL cholesterol levels in current drinkers ( 30698716)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Microalbuminuria ( 31511532)
  • Non-oily fish consumption ( 32066663)
  • Refractive error ( 32231278)
  • Reticulocyte count ( 27863252)
  • Reticulocyte fraction of red cells ( 27863252)
  • Serum alkaline phosphatase levels ( 33339817)
  • Triglyceride levels ( 32203549 32902719 34074324 30698716)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Urinary albumin excretion ( 30220432)
  • Urinary albumin excretion (no hypertensive medication) ( 30220432)
  • Urinary albumin-to-creatinine ratio ( 31630189 30910378 31511532 32600054)
  • Urinary sodium to potassium ratio ( 30910378)
Interacting Genes 76 interacting genes: A2M ANAPC10 ANKS1B APBA2 APBB1 APOE APP BACE1 BDNF C3 C4BPA CACNA1A CALR CANX CAV1 CC2D1A CCN2 CD82 CLU CSRP2 CTSG DAB1 DAB2 DLG4 EGFR ELANE F8 F9 FURIN GIPC1 GTPBP1 GULP1 HNRNPDL HSP90AA1 HSP90B1 ITGB1BP1 KAT5 LIPC LPL LRPAP1 LTF MAPK8IP1 MAPK8IP2 MAPRE1 MDK MMP13 MMP14 MMP15 MMP16 MMP17 MTDH NAB2 NGF NOS1AP NTF3 NTF4 PDGFB PID1 PIGA PLAT PLAUR PMEL PRKACA PTPN11 RIC8B SCN3A SERPINA1 SERPINE1 SHC1 SKIL SNRNP70 SNX17 SRC SYNJ2BP THBS1 WNT3A 19 interacting genes: ACE2 ANXA2 APP HOXC8 HRAS KCNG3 LDLR LRP1 LRP2 LRP8 PEX10 RABAC1 RHOB RIN1 RLIM RNF128 SELP SKIL VLDLR
Entrez ID 4035 9784
HPRD ID 00138 05812
Ensembl ID ENSG00000123384 ENSG00000115234
Uniprot IDs Q07954 Q59FG2 B4DDM3 B4DQ37 B4DTB8 Q15036
PDB IDs 1CR8 1D2L 1J8E 2FYJ 2FYL 2KNX 2KNY 3FOG 3LUI 4GXB 4TKN
Enriched GO Terms of Interacting Partners?
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