LRCH4 and RBBP6

Number of citations of the paper that reports this interaction (PubMedID 18851979)
32

Data Source:
HPRD (two hybrid)

		LRCH4	RBBP6
Description		leucine rich repeats and calponin homology domain containing 4	RB binding protein 6, ubiquitin ligase
Image		No pdb structure
GO Annotations	Cellular Component	PML Body	Nucleus Chromosome Nucleolus Centrosome Cytosol Nuclear Speck Protein-containing Complex
	Molecular Function	Protein Binding	RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Protein Kinase Binding Ubiquitin Protein Ligase Activity
	Biological Process	Nervous System Development	In Utero Embryonic Development DNA Replication Regulation Of DNA Replication MRNA Processing Ubiquitin-dependent Protein Catabolic Process Cellular Response To DNA Damage Stimulus Protein Ubiquitination Multicellular Organism Growth Embryonic Organ Development Somite Development
Pathways			RHOBTB1 GTPase cycle Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Macular thickness ( 30535121) Subcortical volume (MOSTest) ( 32665545)	Adult body size ( 32376654) Body mass index ( 28892062) Body size at age 10 ( 32376654) Brain structure ( 20171287) Chronotype ( 30696823) Low hand grip strength (60 years and older) (EWGSOP) ( 33510174) Obesity-related traits ( 23251661) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		17 interacting genes: CA8 CYB5R3 ELOVL7 HSD17B11 KASH5 KRT40 KRTAP10-7 KRTAP10-8 MDFI NOTCH2NLA PRKAR2B RBBP6 RETREG3 RNASEK RTN4 SIN3A SPOP	41 interacting genes: ACOT13 ANAPC16 APOH ASGR1 CAPZA2 CASK CD81 CLK1 ETS1 EVA1C FAAP24 FBXO7 GLUL GRB2 HP IL4R KHDRBS3 LINC00305 LRCH4 MAD2L2 MDM2 MIR19A MIR19B1 NDUFB9 NEK6 PIAS1 PLG RB1 RBP4 RCC1L RPS14 SMN1 SPP1 TP53 TPT1 UBE2I UPF3B VAV2 YBX1 ZBTB38 ZFYVE9
Entrez ID		4034	5930
HPRD ID		10062	02964
Ensembl ID		ENSG00000077454	ENSG00000122257
Uniprot IDs		O75427	Q7Z6E9
PDB IDs			2C7H 2YSA 2YUR 3ZTG 6E5X
Enriched GO Terms of Interacting Partners?
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