UFSP1 and VAX2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		UFSP1	VAX2
Description		UFM1 specific peptidase 1 (inactive)	ventral anterior homeobox 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Chromatin Nucleus Cytoplasm
	Molecular Function	Molecular_function Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Intronic Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Chromatin DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Biological_process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Ectoderm Development Axonogenesis Central Nervous System Development Visual Perception Dorsal/ventral Axis Specification Wnt Signaling Pathway Neuron Differentiation Forebrain Development Embryonic Eye Morphogenesis Retina Development In Camera-type Eye
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Heart rate increase in response to exercise ( 29497042) Heart rate response to recovery post exercise (20 sec) ( 29497042) Heart rate response to recovery post exercise (30 sec) ( 29497042) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Nonunion in individuals with fractures ( 30680360) Plasminogen activator inhibitor type 1 levels (PAI-1) ( 22990020) Resting heart rate ( 29769521 27798624 20639392)	Acne (severe) ( 24927181) Atopic dermatitis ( 26482879) Corneal astigmatism ( 23322567) Gut microbiota (functional units) ( 27694959) Serum metabolite levels ( 33031748)
Interacting Genes		42 interacting genes: C10orf55 CIDEB CIDEC COG6 CREB5 CSTF2 FAM222B FANCL FOXH1 FOXI1 GLYCTK GPSM3 HNF1B HOXC9 HSF4 INCA1 KRTAP15-1 LASP1 MSRB3 MYOZ3 PITX1 PITX2 POGZ POU6F2 PROP1 PRR22 RAPGEF3 RBPMS2 RUSC1 SMARCC1 SNRPC SPG21 TBX3 TCF7L2 TLX3 UBQLN2 VAC14 VAX2 VGLL3 VPS37C WWOX ZIC1	3 interacting genes: PFDN5 POU6F2 UFSP1
Entrez ID		402682	25806
HPRD ID		18630	05051
Ensembl ID		ENSG00000176125	ENSG00000116035
Uniprot IDs		Q6NVU6	F1T0K5 Q9UIW0
PDB IDs
Enriched GO Terms of Interacting Partners?
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