MCCD1 and LSM1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MCCD1	LSM1
Description		mitochondrial coiled-coil domain 1	LSM1 homolog, mRNA degradation associated
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion	P-body Nucleus Cytoplasm Cytosol Axon Dendrite Neuronal Cell Body Messenger Ribonucleoprotein Complex Lsm1-7-Pat1 Complex
	Molecular Function	Protein Binding	RNA Cap Binding RNA Binding MRNA Binding Protein Binding Pre-mRNA Binding
	Biological Process		Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing RNA Metabolic Process Stem Cell Population Maintenance Negative Regulation Of Neuron Differentiation Histone MRNA Catabolic Process
Pathways			mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease
Drugs
Diseases
GWAS		AIDS progression ( 19115949) Asthma ( 31619474 29273806) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Cervical cancer ( 28806749) Inflammatory bowel disease ( 28067908) Lymphocyte counts ( 32888494) Malaria ( 31844061) Ulcerative colitis ( 28067908)	Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 28991256 22037555 29483656)
Interacting Genes		26 interacting genes: BEX3 BFSP2 CAB39 COX5B FNDC3B KANK2 KRT26 KYNU LMO4 LSM1 MEIS2 MGAT5B MKRN3 MX1 MYL7 P4HA3 PIH1D2 PPP1R16A PRR35 QARS1 RIPPLY1 USHBP1 USP20 ZNF417 ZNF587 ZNF765	34 interacting genes: AGR2 AGR3 BEX5 CLIC1 DAPL1 EXOSC6 EXOSC8 GLUD1 GOLGA7 GRHPR GSTA4 HSP90AA1 LSM2 LSM3 LSM5 LSM6 LSM7 MCCD1 MPDU1 N4BP1 NARS1 NDUFAF3 NSD3 PSMB5 PSMB8 PTPRC RRP1B SMN1 TCL1B TFCP2 TMEM214 UPF2 UXT VPS11
Entrez ID		401250	27257
HPRD ID		17470	06281
Ensembl ID		ENSG00000204511	ENSG00000175324
Uniprot IDs		A0A1U9X802 P59942	A0A0S2Z590 O15116
PDB IDs
Enriched GO Terms of Interacting Partners?
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