LNPEP and FHOD1

Number of citations of the paper that reports this interaction (PubMedID 12677009)
13

Data Source:
HPRD (two hybrid, in vitro)

		LNPEP	FHOD1
Description		leucyl and cystinyl aminopeptidase	formin homology 2 domain containing 1
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GO Annotations	Cellular Component	Extracellular Region Cytoplasm Lysosomal Membrane Cytosol Plasma Membrane Integral Component Of Plasma Membrane Membrane Early Endosome Lumen	Stress Fiber Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Intercalated Disc Membrane Bleb
	Molecular Function	Aminopeptidase Activity Protein Binding Metallopeptidase Activity Zinc Ion Binding Peptide Binding Metalloaminopeptidase Activity	Protein Binding Protein Domain Specific Binding Identical Protein Binding Protein Self-association Actin Filament Binding
	Biological Process	Protein Polyubiquitination Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent Proteolysis Signal Transduction Cell-cell Signaling Female Pregnancy Regulation Of Blood Pressure Peptide Catabolic Process Negative Regulation Of Cold-induced Thermogenesis	Nuclear Migration Cortical Actin Cytoskeleton Organization Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Stress Fiber Assembly Positive Regulation Of Stress Fiber Assembly Actin Filament Network Formation Establishment Of Centrosome Localization
Pathways		Endosomal/Vacuolar pathway Translocation of SLC2A4 (GLUT4) to the plasma membrane Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Acute anterior uveitis (with or without ankylosing spondylitis) ( 25200001) Ankylosing spondylitis ( 23749187) Birdshot chorioretinopathy ( 24957906) Blood protein levels ( 28240269) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Lymphocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494)	Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		32 interacting genes: AGT AQP6 ASGR2 CGRRF1 CTAG1A CTAG1B FAM210B FATE1 FCER1G FHOD1 GGT7 GPR42 GPX8 LCN2 LHFPL5 MMGT1 REEP4 REL SLC2A4 SLC35E3 SLC39A9 SMAD9 SSMEM1 STOM TAS2R19 TCF4 TLCD4 TMEM35A TNKS TNKS2 UBQLN1 UNC93A	22 interacting genes: ACTA1 ACTG1 APC BBS1 BBS2 BBS4 BBS7 CR2 EXOSC8 GRB2 LNPEP NCOA6 NLGN3 PFN2 PPARG PRKG1 RAC1 RANBP2 RNF5 TRIM21 YWHAZ ZMYND8
Entrez ID		4012	29109
HPRD ID		01041	06049
Ensembl ID		ENSG00000113441	ENSG00000135723
Uniprot IDs		Q9UIQ6	A0A068F7M9 Q9Y613
PDB IDs		4P8Q 4PJ6 4Z7I 5C97 5JHQ 5MJ6	3DAD 6XF1 6XF2
Enriched GO Terms of Interacting Partners?
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