LBP and CAMP

Number of citations of the paper that reports this interaction (PubMedID 11544322)
64

Data Source:
HPRD (in vitro)

		LBP	CAMP
Description		lipopolysaccharide binding protein	cathelicidin antimicrobial peptide
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cell Surface Membrane Extracellular Exosome	Extracellular Region Extracellular Space Specific Granule Lumen Specific Granule Cell Projection Extracellular Exosome Tertiary Granule Lumen
	Molecular Function	Lipopolysaccharide Binding Signaling Receptor Binding Protein Binding Lipoteichoic Acid Binding Lipopeptide Binding	Lipopolysaccharide Binding
	Biological Process	Leukocyte Chemotaxis Involved In Inflammatory Response Macrophage Activation Involved In Immune Response Acute-phase Response Cellular Defense Response Opsonization Lipopolysaccharide Transport Lipopolysaccharide-mediated Signaling Pathway Detection Of Molecule Of Bacterial Origin Response To Lipopolysaccharide Negative Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Chemokine Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Interleukin-8 Production Positive Regulation Of Tumor Necrosis Factor Production Macromolecule Localization Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Macrophage Activation Innate Immune Response Positive Regulation Of Cytolysis Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Positive Regulation Of Respiratory Burst Involved In Inflammatory Response Cellular Response To Lipopolysaccharide Cellular Response To Lipoteichoic Acid Positive Regulation Of Neutrophil Chemotaxis	Positive Regulation Of Protein Phosphorylation Innate Immune Response In Mucosa Positive Regulation Of Cell Population Proliferation Antibacterial Humoral Response Defense Response To Bacterium Innate Immune Response Positive Regulation Of Angiogenesis Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Killing By Host Of Symbiont Cells Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cellular Response To Lipopolysaccharide Cellular Response To Peptidoglycan Cellular Response To Interleukin-1 Cellular Response To Interleukin-6 Cellular Response To Tumor Necrosis Factor
Pathways		Toll Like Receptor 4 (TLR4) Cascade Transfer of LPS from LBP carrier to CD14 Regulation of TLR by endogenous ligand Interleukin-4 and Interleukin-13 signaling	Neutrophil degranulation Antimicrobial peptides
Drugs			Selenocysteine
Diseases
GWAS		Basophil percentage of white cells ( 32888494) Blood protein levels ( 29875488) Periodontitis (DPAL) ( 24024966)	Blood protein levels ( 28240269)
Interacting Genes		19 interacting genes: APOA1 BAG6 BST1 C4BPA CAMP CBFA2T2 CD14 CFHR1 CTNNBL1 FTH1 HSPB1 PRDX4 PSMA3 PYCR3 RPS21 SETD1A SMAD3 TRA2A TSC22D4	8 interacting genes: CTSG ELANE FPR2 GPX1 LBP MAPK8 PRTN3 RHOA
Entrez ID		3929	820
HPRD ID		07175	02722
Ensembl ID		ENSG00000129988	ENSG00000164047
Uniprot IDs		P18428 Q8TCF0	A0A384NPR0 J3KNB4 P49913
PDB IDs			2FBS 2FBU 2FCG 2K6O 2LMF 2NA3 4EYC 5NMN 5NNK 5NNM 5NNT 5XNG 5XRX 6BIV 6BIX 6S6M 6S6N
Enriched GO Terms of Interacting Partners?
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