LASP1 and DOK6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LASP1	DOK6
Description		LIM and SH3 protein 1	docking protein 6
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Focal Adhesion Cortical Actin Cytoskeleton	Cytoplasm Cytosol
	Molecular Function	Protein Binding Ion Transmembrane Transporter Activity Cadherin Binding Metal Ion Binding Actin Filament Binding	Protein Binding
	Biological Process	Ion Transport Ion Transmembrane Transport	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of MAPK Cascade
Pathways			RET signaling
Drugs
Diseases
GWAS		Cognitive decline rate in late mild cognitive impairment ( 26252872) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912)	Bone fracture in osteoporosis ( 28580392) Caudate activity during reward ( 28927378) Mean platelet volume ( 31194788) Neonatal total 25-hydroxyvitamin D levels (maternal genetic effect) ( 32047095) Osteoporosis-related phenotypes ( 20548944) Platelet distribution width ( 32888494) Pursuit maintenance gain ( 29064472) Response to cytidine analogues (gemcitabine) ( 24483146) Skin aging (microtopography measurement) ( 28502801)
Interacting Genes		121 interacting genes: ACD ACTA1 ACTB ACTC1 ANKS1A ARHGEF15 ARHGEF16 ARID5A ATXN1 BAG4 BAHD1 BHLHE40 C14orf119 C19orf54 CAMK2A CATSPER1 CDK7 CERCAM CHERP COPS5 CRK CRYBA1 CRYBA2 CSTF2T CTNNA3 CYSRT1 DAZAP2 DMRT3 DNMT1 DOK6 DTX2 EHMT2 EVX2 FAM168A FAM168B FBXO17 FHL3 FOXH1 FXR2 GAS8 GCM2 GOLGA2 GUCD1 HGS HNRNPF HOXA1 INTS11 KRTAP10-8 KRTAP12-4 KRTAP19-3 KRTAP19-4 KRTAP19-6 KRTAP26-1 KRTAP3-2 KRTAP3-3 KRTAP4-2 KRTAP6-2 LENG8 LMO4 LZTS2 MDFI MED25 MGAT5B MKRN3 NOXA1 NUTF2 OTX1 OXER1 PITX1 PLSCR1 POLD1 POT1 POU1F1 PPP1R32 PRKAR2B PRKG1 PRKG2 PRR20A PRR20B PRR20C PRR20D PRR20E PRR35 PSMA3 QRICH1 RBFOX1 RBPMS RBPMS2 REL RHOXF2 RNF38 SEPTIN3 SPAG8 SPRY2 ST3GAL3 STAT3 TCF4 TEKT3 TEKT4 TEKT5 TERF1 TFG THAP1 TINF2 TLX3 TNS2 TRIM27 TRIP13 UFSP1 UHRF1 VAC14 VEZF1 VGLL3 VPS37C WWOX YES1 YTHDF1 ZBTB9 ZC2HC1A ZC3H10 ZYX	21 interacting genes: ABHD11 ARID5A C1orf94 CD226 CRYBB3 EGFR ERBB2 FAM86C1P LASP1 LGALS14 METTL27 NTRK3 PRR22 RBPMS RET RUSC1 SLC30A6 TBX15 TLE5 USP54 YPEL3
Entrez ID		3927	220164
HPRD ID		04229	13244
Ensembl ID		ENSG00000002834	ENSG00000206052
Uniprot IDs		A0A024R1S8 B4DIC4 Q14847	Q6PKX4
PDB IDs		3I35
Enriched GO Terms of Interacting Partners?
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