LAMA2 and SNAPIN

Number of citations of the paper that reports this interaction (PubMedID 23414517)
13

Data Source:
BioGRID (two hybrid)

		LAMA2	SNAPIN
Description		laminin subunit alpha 2	SNAP associated protein
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Neuromuscular Junction Sarcolemma Synaptic Cleft Dendritic Spine Collagen-containing Extracellular Matrix	Golgi Membrane Acrosomal Vesicle Manchette Lysosomal Membrane Synaptic Vesicle Secretory Granule Synaptic Vesicle Membrane BLOC-1 Complex Synapse Perinuclear Region Of Cytoplasm BORC Complex Axon Cytoplasm
	Molecular Function	Signaling Receptor Binding Structural Molecule Activity Extracellular Matrix Structural Constituent	SNARE Binding Protein Binding
	Biological Process	Cell Adhesion Axon Guidance Muscle Organ Development Animal Organ Morphogenesis Tissue Development Schwann Cell Differentiation Regulation Of Cell Adhesion Regulation Of Cell Migration Positive Regulation Of Synaptic Transmission, Cholinergic Maintenance Of Blood-brain Barrier Regulation Of Embryonic Development	Intracellular Protein Transport Lysosome Organization Lysosomal Lumen Acidification Neurotransmitter Secretion Anterograde Axonal Transport Retrograde Axonal Transport Endosome To Lysosome Transport Negative Regulation Of Neuron Projection Development Synaptic Vesicle Exocytosis Synaptic Vesicle Maturation Neuron Projection Development Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Lysosome Localization Melanosome Organization Cellular Protein-containing Complex Localization Regulation Of Protein Binding Synaptic Vesicle Transport Anterograde Synaptic Vesicle Transport Protein Maturation Terminal Button Organization Autophagosome Maturation Late Endosome To Lysosome Transport Positive Regulation Of Late Endosome To Lysosome Transport Regulation Of Synaptic Vesicle Exocytosis
Pathways		Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans MET activates PTK2 signaling EGR2 and SOX10-mediated initiation of Schwann cell myelination	Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Axial length ( 24144296) Body mass index ( 20397748) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Height ( 31562340) High myopia ( 31816047) Hyperopia ( 25233373) Metabolite levels ( 23823483) Myopia ( 27182965 25233373) Night sleep phenotypes ( 27126917) Periodontal disease-related phenotype (Socransky) ( 24347629) Refractive error ( 23396134) Retinal detachment or retinal break ( 31816047) Serum bilirubin levels x Mediterranean diet adherence interaction in metabolic syndrome ( 30621171) Sleep duration (short sleep) ( 30846698) Smoking status (ever vs never smokers) ( 30643258) Spherical equivalent (joint analysis main effects and education interaction) ( 27020472) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Tea consumption ( 31046077)
Interacting Genes		4 interacting genes: DAG1 RPSA SNAPIN TRIM63	104 interacting genes: ABI2 ACTN2 ATG14 ATP1A1 BANP BFSP1 BFSP2 BIN1 BLOC1S1 BLOC1S2 BLOC1S4 BLOC1S5 BLOC1S6 BNIPL C20orf202 CCDC102B CDC42BPA CEP170 CMYA5 CSNK1D DDR1 DENND1C DES DNM2 DOCK9 DST DTNBP1 DYSF EBAG9 EEF1G ELP1 ENO3 ENTHD1 EXOC1 EXOC7 FAM114A1 FSD2 GPRASP1 HAP1 HMGB2 IKBIP IMMT INSYN1 KANK2 KAT5 KAT7 KIF5C KPNB1 KRT10 KRT15 KRT16 KRT17 KRT19 KRT20 KRT24 KRT26 KRT27 LAMA2 LAMC1 LMNB1 LRP12 MACF1 MAPK14 MET MTNR1A MYH14 MYH3 MYH7 NECAB2 NEDD9 NME7 NUP62CL PCYT1A PLAC9 PLEC PRKACA RABEP1 RABGEF1 RETREG1 RGS7 RNF13 SHBG SKA1 SMAD2 SMG1 SNAP23 SNAP25 SPAG5 SPP1 SPTB SPTBN1 ST7 TFIP11 TOMM70 TPM1 TPM2 TPM3 TPM4 TRIM63 TRPV1 TSG101 WASHC3 YWHAE YWHAZ
Entrez ID		3908	23557
HPRD ID		01125	06111
Ensembl ID		ENSG00000196569	ENSG00000143553
Uniprot IDs		P24043 Q59H37	O95295
PDB IDs		4YEP 4YEQ
Enriched GO Terms of Interacting Partners?
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