RND3 and ARHGAP5

Number of citations of the paper that reports this interaction (PubMedID 12842009)
86

Data Source:
BioGRID (two hybrid, affinity chromatography technology, pull down)
HPRD (in vitro, two hybrid, in vivo)

		RND3	ARHGAP5
Description		Rho family GTPase 3	Rho GTPase activating protein 5
Image
GO Annotations	Cellular Component	Golgi Membrane Cytoskeleton Plasma Membrane Focal Adhesion Cell Cortex Cytoplasmic Vesicle Cell Projection	Cytoplasm Endoplasmic Reticulum Cytosol Plasma Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding Protein Kinase Binding	GTPase Activity GTPase Activator Activity Protein Binding GTP Binding SH2 Domain Binding
	Biological Process	Actin Filament Organization Cell Adhesion Establishment Or Maintenance Of Cell Polarity Small GTPase Mediated Signal Transduction Regulation Of Cell Shape Cell Migration Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization	Cell Adhesion Rho Protein Signal Transduction Mammary Gland Development Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		RND3 GTPase cycle	RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RHOD GTPase cycle RHOQ GTPase cycle RHOG GTPase cycle RHOJ GTPase cycle RAC3 GTPase cycle RHOF GTPase cycle RND3 GTPase cycle RND2 GTPase cycle RND1 GTPase cycle
Drugs		Guanosine-5'-Triphosphate
Diseases
GWAS		Arterial stiffness (brachial-ankle pulse wave velocity) ( 32790701) Daytime nap ( 33568662) Endometriosis ( 23472165) Esophageal adenocarcinoma x gastroesophageal reflux disease interaction ( 29551738) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Neonatal total 25-hydroxyvitamin D levels (fetal genetic effect) ( 32047095) Platelet count ( 31217584) Reticulocyte fraction of red cells ( 32888494) Type 2 diabetes ( 22238593) Urinary metabolite levels in chronic kidney disease ( 29545352)	Asthma ( 29273806)
Interacting Genes		10 interacting genes: ARHGAP5 C14orf119 CDH5 CIT CPLANE2 GCH1 PLXNB1 ROCK1 SKP2 UBXN11	12 interacting genes: ADRB2 ITGA5 ITGB1 PTK2B PTPN18 RASA1 RHOA RND1 RND2 RND3 SMURF2 SUZ12
Entrez ID		390	394
HPRD ID		04233	04060
Ensembl ID		ENSG00000115963	ENSG00000100852
Uniprot IDs		B2R838 P61587	Q13017
PDB IDs		1M7B 2V55 4BG6	2EE4 2EE5 5U4V
Enriched GO Terms of Interacting Partners?
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