C8orf86 and WRN

C8orf86

WRN

Description chromosome 8 open reading frame 86 WRN RecQ like helicase
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Birth weight ( 31043758)
  • Erosive tooth wear (severe vs non-severe) ( 29898447)
  • Erosive tooth wear (severe vs none or mild) ( 29898447)
  • Response to cognitive-behavioural therapy in anxiety disorder ( 26989097)
  • Chronotype ( 30696823)
  • Cough in response to angiotensin-converting enzyme inhibitor drugs ( 28084903)
  • Daytime sleep phenotypes ( 27126917)
  • Exercise treadmill test traits ( 17903301)
  • Fasting glucose change (long-term) ( 31263163)
  • Intelligence (MTAG) ( 29326435)
  • Lifespan ( 25918517)
  • Logical memory (delayed recall) in mild cognitive impairment ( 29274321)
  • Logical memory (immediate recall) in mild cognitive impairment ( 29274321)
  • Metabolite levels ( 23823483)
  • Morning person ( 30696823)
Interacting Genes 2 interacting genes: UBXN8 WRN 37 interacting genes: ADRB3 ATM ATRX BARD1 BLM BRCA1 C8orf86 CDKN2A FEN1 H2AX HTR5A MDC1 MDM2 MIB1 PARP1 PCNA POLB POLD2 POLK POLR1C PRKAR1B PRKDC RAD1 RAD51 RAD52 RAD54B RAD9A RPA1 SUMO1 SUMO2 TERF2 TP53 UBXN8 VCP WRNIP1 XRCC5 XRCC6
Entrez ID 389649 7486
HPRD ID 13474 05212
Ensembl ID ENSG00000196166 ENSG00000165392
Uniprot IDs Q6ZUL3 Q14191
PDB IDs 2AXL 2DGZ 2E1E 2E1F 2FBT 2FBV 2FBX 2FBY 2FC0 3AAF 6TYV 6YHR
Enriched GO Terms of Interacting Partners?
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