KTN1 and CLEC4C

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KTN1	CLEC4C
Description		kinectin 1	C-type lectin domain family 4 member C
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane	Plasma Membrane Integral Component Of Membrane Secretory Granule Membrane Tertiary Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	RNA Binding Protein Binding Kinesin Binding Cadherin Binding	Protein Binding Carbohydrate Binding Metal Ion Binding
	Biological Process	Microtubule-based Movement Protein Transport	Adaptive Immune Response Innate Immune Response
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) RHO GTPases activate KTN1 Post-translational protein phosphorylation RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RHOG GTPase cycle RND3 GTPase cycle RND2 GTPase cycle	Dectin-2 family Neutrophil degranulation
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Early spontaneous preterm birth ( 31194736) Lean body mass ( 28552196) Neurofibrillary tangles ( 31497858) Plasma anti-thyroglobulin levels ( 29678681) Subcortical brain region volumes ( 25607358)	Blood protein levels ( 30072576)
Interacting Genes		30 interacting genes: ABI1 BNIP3 CD3G CD68 CDC42 CLEC4C CLEC7A EEF1D FFAR2 IKBKE INPP5E KIF5B KIR2DL3 LHFPL5 M6PR MEOX2 MFSD14B PDCD1LG2 PLEKHA5 RAC1 RHOA RHOG SGTA SIRPA STOM SUSD3 SYNE4 SYNPR TMEM179B UBE2I	3 interacting genes: CLDN22 KTN1 MAL
Entrez ID		3895	170482
HPRD ID		02661	09453
Ensembl ID		ENSG00000126777	ENSG00000198178
Uniprot IDs		A0A024R663 Q86UP2	Q8WTT0
PDB IDs			3WBP 3WBQ 3WBR 4ZES 4ZET
Enriched GO Terms of Interacting Partners?
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