LYSMD1 and DUSP4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LYSMD1	DUSP4
Description		LysM domain containing 1	dual specificity phosphatase 4
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GO Annotations	Cellular Component	Nucleoplasm	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Protein Binding	Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/threonine Phosphatase Activity Phosphatase Activity MAP Kinase Tyrosine/serine/threonine Phosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity MAP Kinase Serine/threonine Phosphatase Activity
	Biological Process		Endoderm Formation Dephosphorylation Negative Regulation Of MAPK Cascade Negative Regulation Of ERK1 And ERK2 Cascade
Pathways			RAF-independent MAPK1/3 activation ERKs are inactivated Negative regulation of MAPK pathway
Drugs
Diseases
GWAS			Gestational age at birth (maternal effect) ( 28598419) Postoperative complication after cardiac surgery ( 30678657) Prostate cancer ( 33293427) Response to statin therapy ( 20339536) Spontaneous preterm birth (maternal effect) ( 28598419)
Interacting Genes		11 interacting genes: DUSP4 GOLGA2 GOLGA6L9 KRT34 MTUS2 PAX6 RINT1 TCF12 TFIP11 TRAF2 TRIM69	21 interacting genes: APP ATP1A3 CRMP1 GORASP2 GRIN1 GRIN2D IDO1 LYSMD1 LYSMD2 LZTS2 MAPK1 MAPK14 MAPK3 MAPK8 MAPK9 NOXA1 PLEKHF2 TEPSIN TRAF1 ZNF426 ZNF655
Entrez ID		388695	1846
HPRD ID		18017	04123
Ensembl ID		ENSG00000163155	ENSG00000120875
Uniprot IDs		Q96S90	Q13115
PDB IDs		2DJP	3EZZ
Enriched GO Terms of Interacting Partners?
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